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Mcpt2
Gene Detail
Symbol

Name
ID
Mcpt2
mast cell protease 2
MGI:96938
Synonyms
Mcp-2, MMCP-2, MMCP-2
Feature Type
protein coding gene
Genetic Map
Chromosome 14
28.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr14:56042123-56044634 bp, + strand
From Ensembl annotation of GRCm38

  2512 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: trypsin
Gene Tree: Mcpt2
Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Mcpt2 interacts with 35 markers (Mir23a, Mir23b, Mir27a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process protein processing, proteolysis
Component extracellular space, intracellular
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
cDNA source data(51)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(56) Genomic(5) cDNA(51)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000022226 (Evidence)
Entrez Gene 17225 (Evidence)
UniGene 4409
DFCI TC1583216
DoTS DT.87069495
EC 3.4.21.-
Consensus CDS Project CCDS27139.1
International Mouse Phenotyping Consortium Status Mcpt2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022226 Ensembl Gene Model | MGI Sequence Detail 2512 C57BL/6J ±  kb
transcript ENSMUST00000015576 Ensembl | MGI Sequence Detail 971 Not Applicable 
polypeptide ENSMUSP00000015576 Ensembl | MGI Sequence Detail 244 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(90 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000010903 mast cell protease 2
References
(Earliest) J:10169 Serafin WE, et al., Identification and molecular cloning of a novel mouse mucosal mast cell serine protease. J Biol Chem. 1990 Jan 5;265(1):423-9
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(34)
Other
accession IDs
MGD-MRK-12144, MGD-MRK-12152

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory