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Maob
Gene Detail
Symbol

Name
ID
Maob
monoamine oxidase B
MGI:96916
Synonyms
6330414K01Rik, MAO-B
Feature Type
protein coding gene
Genetic Map
Chromosome X
11.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
ChrX:16709282-16817366 bp, - strand
From VEGA annotation of GRCm38

  108085 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20251  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MAOB
Gene Tree: Maob

Human
homologs
MAOB, monoamine oxidase B
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 4129
neXtProt AC: NX_P27338

Human Chr (Location): Xp11.23; chrX:43766610-43882475 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(2) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit increased brain levels and urinary excretion of beta-phenylethylamine, stress-induced hyperactivity, and decreased susceptibility to dopaminergic neuron neurotoxicity.
 
Interactions
Maob interacts with 201 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (8 records)
Data Summary: Results (274)    Tissues (189)    Images (80)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 23
RNA in situ 247
Western blot 4
cDNA source data(47)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100494267    NEW 
Molecular
reagents
All nucleic(48) cDNA(48)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000016927 (Evidence)
Ensembl Gene Model ENSMUSG00000040147 (Evidence)
Entrez Gene 109731 (Evidence)
UniGene 241656
DFCI TC1577658
DoTS DT.101299578
NIA Mouse Gene Index U039281
EC 1.4.3.4
Consensus CDS Project CCDS40882.1
International Mouse Phenotyping Consortium Status Maob
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016927 VEGA Gene Model | MGI Sequence Detail 108085 C57BL/6J ±  kb
transcript OTTMUST00000041060 VEGA | MGI Sequence Detail 2411 Not Applicable 
polypeptide OTTMUSP00000018395 VEGA | MGI Sequence Detail 520 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(1) : SNPs within 2kb(246 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002937 Amine oxidase
InterPro IPR001613 Flavin amine oxidase
Protein Ontology PR:000010115 amine oxidase [flavin-containing] B
References
(Earliest) J:10089 Derry JM, et al., Localization of monoamine oxidase A and B genes on the mouse X chromosome. Nucleic Acids Res. 1989 Oct 25;17(20):8403
(Latest) J:211207 Wang CC, et al., Serotonin receptor 6 mediates defective brain development in monoamine oxidase A-deficient mouse embryos. J Biol Chem. 2014 Mar 21;289(12):8252-63
All references(53)
Other
accession IDs
MGD-MRK-12112, MGI:2443774

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory