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Ly9
Gene Detail
 Symbol
Name
ID
Ly9
lymphocyte antigen 9
MGI:96885
Synonyms CD229, Lgp100, SLAMF3, T100
Feature Type protein coding gene
Genetic Map
Chromosome 1
79.54 cM
Detailed Genetic Map ± 1 cM


Mapping data(45)
Sequence Map
Chr1:171588624-171607410 bp, - strand
From VEGA annotation of GRCm38

  18787 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1759  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

Gene Tree: Ly9

Human
homologs
Human Homolog LY9, lymphocyte antigen 9
NCBI Gene ID 4063
neXtProt AC  NX_Q9HBG7
Human Synonyms  CD229, hly9, mLY9, SLAMF3
Human Chr (Location)  1q23.3; chr1:160796074-160828255 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
This locus controls an antigen on thymocytes, lymphocytes and bone marrow cells. The a allele determines Ly9.1 antigen in A/J, 129/Re, BALB/c and C3H/He; the b allele determines antigen Ly9.2 in the C57 family of strains, HTI/Go, MA/My, F/St and C58/Lw. Null mutants are viable, healthy and fertile.
 
Interactions
Ly9 interacts with 88 markers (Mir10a, Mir29a, Mir30c-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process cell adhesion
Component integral component of membrane, membrane
Function receptor activity
External Resources: FuncBase
Expression
cDNA source data(53)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(69) Genomic(14) cDNA(54) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000016916 (Evidence)
Ensembl Gene ModelENSMUSG00000004707 (Evidence)
Entrez Gene17085 (Evidence)
UniGene560
DFCITC1580063, TC1609336, TC1617741
DoTSDT.101737449, DT.110929981, DT.487450, DT.91361457, DT.91386897
NIA Mouse Gene IndexU022058
Consensus CDS ProjectCCDS35779.1, CCDS69978.1
International Mouse Knockout Project StatusLy9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016916 VEGA Gene Model | MGI Sequence Detail 18787 C57BL/6J ±  kb
transcript OTTMUST00000041044 VEGA | MGI Sequence Detail 2488 Not Applicable 
polypeptide OTTMUSP00000018387 VEGA | MGI Sequence Detail 654 Not Applicable 

For the selected sequences
All sequences(72) RefSeq(5) UniProt(9)
Polymorphisms RFLP(1) : SNPs within 2kb(219 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR013106 Immunoglobulin V-set
InterPro IPR015631 Signalling lymphocyte activation molecule family receptors
Protein Ontology PR:000001842 T-lymphocyte surface antigen Ly-9
References (Earliest) J:6136 Durda PJ, et al., T100: a new murine cell surface glycoprotein detected by anti-Lyt-2.1 serum. J Immunol. 1979 Apr;122(4):1407-12
(Latest) J:190814 Sintes J, et al., Cutting Edge: Ly9 (CD229), a SLAM Family Receptor, Negatively Regulates the Development of Thymic Innate Memory-like CD8+ T and Invariant NKT Cells. J Immunol. 2013 Jan 1;190(1):21-6
All references(69)
Other
accession IDs
MGD-MRK-12008, MGD-MRK-12051, MGI:2138373

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory