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Ly6c1 Gene Detail
Summary
  • Symbol
    Ly6c1
  • Name
    lymphocyte antigen 6 complex, locus C1
  • Synonyms
    Ly6c, Ly-6C
  • Feature Type
    protein coding gene
  • IDs
    MGI:96882
    NCBI Gene: 17067
  • Member of
    Ly6 cluster
Location & Maps
more
  • Sequence Map
    Chr15:75044018-75048830 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4813 bp   ±  kb flank

  • Genome Browsers
Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    21 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    3
  • Radiation induced
    2
  • Genomic Mutations
    5 involving Ly6c1
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045162 VEGA Gene Model | MGI Sequence Detail 4813 C57BL/6J ±  kb
transcript OTTMUST00000118677 VEGA | MGI Sequence Detail 784 Not Applicable  
polypeptide OTTMUSP00000066236 VEGA | MGI Sequence Detail 147 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    52 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000029071 lymphocyte antigen 6C1
  • InterPro Domains
    IPR018363 CD59 antigen, conserved site
    IPR016054 Ly-6 antigen/uPA receptor-like
Molecular
Reagents
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  • All nucleic 115
    Genomic 4
    cDNA 111

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-12005, MGD-MRK-12048, MGI:2145928, MGI:2145929
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 2
    Phenotypes 21
  • Earliest
    J:8979 Palfree RG, et al., N-terminal and cDNA characterization of murine lymphocyte antigen Ly-6C.2. J Immunol. 1988 Jan 1;140(1):305-10
  • Latest
    J:191745 Ramachandran P, et al., Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis. Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):E3186-95

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory