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Alad Gene Detail
Summary
  • Symbol
    Alad
  • Name
    aminolevulinate, delta-, dehydratase
  • Synonyms
    Lv
  • Feature Type
    protein coding gene
  • IDs
    MGI:96853
    NCBI Gene: 17025
  • Gene Overview
    MyGene.info: ALAD
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:62509169-62519918 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 33.17 cM
  • Mapping Data
    18 experiments
Strain
Comparison
more
  • SNPs within 2kb
    132 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96853
protein coding gene Chr4:62505984-62520063 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028356
protein coding gene Chr4:61492022-61504318 (-)
A/J MGP_AJ_G0028317
protein coding gene Chr4:59265346-59278814 (-)
AKR/J MGP_AKRJ_G0028266
protein coding gene Chr4:60911913-60923248 (-)
BALB/cJ MGP_BALBcJ_G0028337
protein coding gene Chr4:59444319-59455731 (-)
C3H/HeJ MGP_C3HHeJ_G0028055
protein coding gene Chr4:61414081-61425328 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028777
protein coding gene Chr4:63609549-63621677 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026083
protein coding gene Chr4:56552678-56567530 (-)
CAST/EiJ MGP_CASTEiJ_G0027491
protein coding gene Chr4:59356067-59366606 (-)
CBA/J MGP_CBAJ_G0028023
protein coding gene Chr4:65810016-65824547 (-)
DBA/2J MGP_DBA2J_G0028173
protein coding gene Chr4:59128424-59142584 (-)
FVB/NJ MGP_FVBNJ_G0028137
protein coding gene Chr4:58375506-58387533 (-)
LP/J MGP_LPJ_G0028269
protein coding gene Chr4:61770727-61781373 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028164
protein coding gene Chr4:68935647-68949073 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028813
protein coding gene Chr4:61012968-61024264 (-)
PWK/PhJ MGP_PWKPhJ_G0027218
protein coding gene Chr4:57603682-57617053 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027047
protein coding gene Chr4:58461457-58471770 (-)
WSB/EiJ MGP_WSBEiJ_G0027571
protein coding gene Chr4:60993572-61005108 (-)



Homology
more
  • Human Ortholog
    ALAD, aminolevulinate dehydratase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ALAD, aminolevulinate dehydratase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ALADH, PBGS
  • Links
    NCBI Gene ID: 210
    neXtProt AC: NX_P13716
    UniProt: P13716

  • Chr Location
    9q32; chr9:113386312-113401338 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ALAD associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028393 Ensembl Gene Model | MGI Sequence Detail 10750 C57BL/6J ±  kb
transcript ENSMUST00000107444 Ensembl | MGI Sequence Detail 1247 Not Applicable  
polypeptide ENSMUSP00000103068 Ensembl | MGI Sequence Detail 330 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    Genomic 14
    cDNA 21

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-11931
References
more
  • Summaries
    All 64
    Developmental Gene Expression 7
    Gene Ontology 11
    Phenotypes 9
  • Earliest
    J:14972 Russell RL, et al., Genetic control of hepatic delta-aminolevulinate dehydratase in mice. Genetics. 1963 Aug;48:1033-39
  • Latest
    J:198500 Nakahara M, et al., Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm Genome. 2013 Jun;24(5-6):228-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory