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Anxa1
Gene Detail
 Symbol
Name
ID
Anxa1
annexin A1
MGI:96819
Synonyms Anx-1, Anx-A1, C430014K04Rik, Lpc1, Lpc-1
Feature Type protein coding gene
Genetic Map
Chromosome 19
13.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(20)
Sequence Map
Chr19:20373428-20390944 bp, - strand
From VEGA annotation of GRCm38

  17517 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:563  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Anxa1

Human
homologs
Human Homolog ANXA1, annexin A1
NCBI Gene ID 301
neXtProt AC  NX_P04083
Human Synonyms  ANX1, LPC1
Human Chr (Location)  9q21.13; chr9:73151865-73170391 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mutations in this gene result in increased inflammatory response and decreased macrophage activity.
 
Phenotype Images(1)
Interactions
Anxa1 interacts with 65 markers (Mir1a-1, Mir1a-2, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (66 annotations)
Process alpha-beta T cell differentiation, arachidonic acid secretion, ...
Component cell projection, cell surface, ...
Function annealing helicase activity, calcium-dependent phospholipid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (171)    Tissues (45)    Images (38)
Theiler Stages: 19, 22, 23, 28
Assay TypeResults
RNA in situ 169
RT-PCR 2
cDNA source data(330)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(336) Genomic(3) cDNA(330) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000035986 (Evidence)
Ensembl Gene ModelENSMUSG00000024659 (Evidence)
Entrez Gene16952 (Evidence)
UniGene248360
DFCITC1573220, TC1598724
DoTSDT.101364535, DT.101384298, DT.536818
NIA Mouse Gene IndexU038902
Consensus CDS ProjectCCDS29692.1
International Mouse Knockout Project StatusAnxa1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035986 VEGA Gene Model | MGI Sequence Detail 17517 C57BL/6J ±  kb
transcript OTTMUST00000092342 VEGA | MGI Sequence Detail 1674 Not Applicable 
polypeptide OTTMUSP00000051013 VEGA | MGI Sequence Detail 346 Not Applicable 

For the selected sequences
All sequences(67) RefSeq(2) UniProt(6)
Polymorphisms All PCR and RFLP(3) : PCR(2) RFLP(1) SNPs within 2kb(385 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001464 Annexin
InterPro IPR018502 Annexin repeat
InterPro IPR018252 Annexin repeat, conserved site
InterPro IPR002388 Annexin, type I
Protein Ontology PR:000004071 annexin A1
References (Earliest) J:9543 Sakata T, et al., Mouse lipocortin I cDNA. Nucleic Acids Res. 1988 Dec 23;16(24):11818
(Latest) J:209746 Akasheh RT, et al., Increased adiposity in annexin A1-deficient mice. PLoS One. 2013;8(12):e82608
All references(109)
Other
accession IDs
MGD-MRK-11869, MGD-MRK-11870, MGI:2442613

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory