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Mycl
Gene Detail
 Symbol
Name
ID
Mycl
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
MGI:96799
Synonyms bHLHe38, L-myc, Lmyc1, Lmyc-1, Mycl1
Feature Type protein coding gene
Genetic Map
Chromosome 4
57.36 cM
Detailed Genetic Map ± 1 cM


Mapping data(40)
Sequence Map
Chr4:122995652-123002485 bp, + strand
From VEGA annotation of GRCm38

  6834 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3921  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: myc protein
Gene Tree: Mycl

Human
homologs
Human Homolog MYCL, v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NCBI Gene ID 4610
neXtProt AC  NX_P12524
Human Synonyms  bHLHe38, LMYC, MYCL1
Human Chr (Location)  1p34.2; chr1:39895424-39902015 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
 
Mice homozygous for a targeted null allele are viable, fertile and apparently healthy with no congenital defects or gross morphological/cellular alterations of the CNS, lung, kidney and GI tract.
 
Interactions
Mycl interacts with 255 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process regulation of transcription, DNA-templated
Component nucleus
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (26 records)
Data Summary: Results (404)    Tissues (169)    Images (38)
Theiler Stages: 2, 3, 4, 5, 15, 17, 19, 21, 23, 26, 27, 28
Assay TypeResults
RNA in situ 309
Northern blot 42
RT-PCR 51
RNase protection 2
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(30) Genomic(6) cDNA(12) Primer pair(5) Other(7)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000008931 (Evidence)
Ensembl Gene ModelENSMUSG00000028654 (Evidence)
Entrez Gene16918 (Evidence)
DFCITC1579235
DoTSDT.101378678, DT.528644
NIA Mouse Gene IndexU042574
Consensus CDS ProjectCCDS18606.1
International Mouse Knockout Project StatusMycl
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008931 VEGA Gene Model | MGI Sequence Detail 6834 C57BL/6J ±  kb
transcript OTTMUST00000020287 VEGA | MGI Sequence Detail 3293 Not Applicable 
polypeptide OTTMUSP00000009306 VEGA | MGI Sequence Detail 368 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(6) UniProt(3)
Polymorphisms All PCR and RFLP(13) : PCR(1) RFLP(12) SNPs within 2kb(18 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
InterPro IPR002418 Transcription regulator Myc
InterPro IPR012682 Transcription regulator Myc, N-terminal
Protein Ontology PR:000010810 protein L-Myc-1
References (Earliest) J:8211 Zimmerman KA, et al., Differential expression of myc family genes during murine development. Nature. 1986 Feb 27-Mar 5;319(6056):780-3
(Latest) J:206430 Kc W, et al., L-Myc expression by dendritic cells is required for optimal T-cell priming. Nature. 2014 Feb 9;
All references(97)
Other
accession IDs
MGD-MRK-11830, MGD-MRK-11832, MGI:2140581

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory