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Lalba
Gene Detail
 Symbol
Name
ID
Lalba
lactalbumin, alpha
MGI:96742
Synonyms lactalbumin alpha
Feature Type protein coding gene
Genetic Map
Chromosome 15
54.48 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:98480400-98482683 bp, - strand
From NCBI annotation of GRCm38

  2284 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1720  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Gene Tree: Lalba

Human
homologs
Human Homolog LALBA, lactalbumin, alpha-
NCBI Gene ID 3906
neXtProt AC  NX_P00709
Human Chr (Location)  12q13; chr12:48567684-48571745 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Radiation induced(1) Targeted(4)
Genomic Mutations involving Lalba (1)
Incidental mutations (data from APF )
 
Homozygous null females are unable to nurse their offspring and have increased milk viscosity.
 
Interactions
Lalba interacts with 62 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process lactose biosynthetic process
Component extracellular region
Function calcium ion binding, lactose synthase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (178)    Tissues (145)    Images (36)
Theiler Stages: 22, 23, 28
Assay TypeResults
RNA in situ 132
RT-PCR 46
cDNA source data(161)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(167) Genomic(4) cDNA(161) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000022991 (Evidence)
Entrez Gene16770 (Evidence)
UniGene5074
DFCITC1576870
DoTSDT.40167173
NIA Mouse Gene IndexU036620
PDB1NHE, 1NKH, 1NMM, 1NQI, 1NWG, 1OQM, 1PZY, 1YRO, 2FYC, 2FYD, 1NF5, 1O23
Consensus CDS ProjectCCDS27795.1
International Mouse Knockout Project StatusLalba
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 16770 NCBI Gene Model | MGI Sequence Detail 2284 C57BL/6J ±  kb
transcript NM_010679 RefSeq | MGI Sequence Detail 733 BALB/c 
polypeptide P29752 UniProt | EBI | MGI Sequence Detail 143 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001916 Glycoside hydrolase, family 22
InterPro IPR019799 Glycoside hydrolase, family 22, conserved site
InterPro IPR000545 Lactalbumin
InterPro IPR023346 Lysozyme-like domain
Protein Ontology PR:000009649 alpha-lactalbumin
Graphical View of Protein Domain Structure
References (Earliest) J:129 Vilotte JL, et al., Sequence of the murine alpha-lactalbumin-encoding cDNA: interspecies comparison of the coding frame and deduced pre-protein. Gene. 1992 Mar 15;112(2):251-5
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(39)
Other
accession IDs
MGD-MRK-11732, MGI:2146204

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory