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l7Rn6
Gene Detail
Symbol

Name
ID
l7Rn6
lethal, Chr 7, Rinchik 6
MGI:96738
Synonyms
0610007P06Rik, 1110002N09Rik, Hikeshi, l(7)6Rn
Feature Type
protein coding gene
Genetic Map
Chromosome 7
50.40 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr7:89917529-89941199 bp, - strand
From VEGA annotation of GRCm38

  23671 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6908  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: l7Rn6

Human
homologs
Human Homolog C11orf73, chromosome 11 open reading frame 73
NCBI Gene ID 51501
neXtProt AC  NX_Q53FT3
Human Synonyms  Hikeshi, HSPC179, L7RN6, OPI10
Human Chr (Location)  11q14.2; chr11:86302211-86345943 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(63) : Chemically induced (ENU)(1) Gene trapped(61) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU-induced mutation die prenatally or neonatally, and exhibit cyanoisis with a significant emphysematous phenotype at birth. The secretory apparatus in Clara cells is also affected.
 
Interactions
l7Rn6 interacts with 197 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cellular response to heat, Golgi organization, ...
Component cell junction, cytoplasm, ...
Function Hsp70 protein binding, protein transporter activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(61)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(68) Genomic(2) cDNA(61) Other(5)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000023022 (Evidence)
Ensembl Gene ModelENSMUSG00000062797 (Evidence)
Entrez Gene67669 (Evidence)
UniGene28679
DFCITC1577043, TC1601941, TC1630653
NIA Mouse Gene IndexU127588
Consensus CDS ProjectCCDS21445.1
International Mouse Knockout Project Statusl7Rn6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023022 VEGA Gene Model | MGI Sequence Detail 23671 C57BL/6J ±  kb
transcript OTTMUST00000055454 VEGA | MGI Sequence Detail 2205 Not Applicable 
polypeptide OTTMUSP00000026557 VEGA | MGI Sequence Detail 197 Not Applicable 

For the selected sequences
All sequences(65) RefSeq(15) UniProt(5)
Polymorphisms
SNPs within 2kb(150 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008493 Protein of unknown function DUF775
References
(Earliest) J:12917 Rinchik EM, et al., N-ethyl-N-nitrosourea-induced prenatally lethal mutations define at least two complementation groups within the embryonic ectoderm development (eed) locus in mouse chromosome 7. Mamm Genome. 1993;4(7):349-53
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)
Other
accession IDs
MGD-MRK-11694, MGD-MRK-11726, MGI:1913365, MGI:1914919

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory