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Krt9
Gene Detail
Symbol

Name
ID
Krt9
keratin 9
MGI:96696
Synonyms
K9, Krt1-9
Feature Type
protein coding gene
Genetic Map
Chromosome 11
63.43 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:100186781-100193246 bp, - strand
From VEGA annotation of GRCm38

  6466 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:138337  Vertebrate Homology Class
1 mouse; 1 rat

HCOP human homology predictions: KRT9
Gene Tree: Krt9

Human
homologs
KRT9, keratin 9, type I
Orthology source: HGNC

IDs:
NCBI Gene ID: 3857
neXtProt AC: NX_P35527

Human Synonyms: CK-9, EPPK, K9

Human Chr (Location): 17q21.2; chr17:41565841-41572058 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human KRT9

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Genomic Mutations involving Krt9 (1)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele exhibit hyperpigmented calluses on the footpad with acanthosis, hyperkeratosis, thick epidermis and increased keratinocyte proliferation.
 
Interactions
Krt9 interacts with 56 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process spermatogenesis
Component intermediate filament, keratin filament, ...
Function structural molecule activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(2)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(3) cDNA(2) Other(1)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000002544 (Evidence)
Ensembl Gene Model ENSMUSG00000051617 (Evidence)
Entrez Gene 107656 (Evidence)
UniGene 445335
DFCI TC1592655
DoTS DT.102553891
NIA Mouse Gene Index U051340
Consensus CDS Project CCDS25412.1
International Mouse Phenotyping Consortium Status Krt9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002544 VEGA Gene Model | MGI Sequence Detail 6466 C57BL/6J ±  kb
transcript OTTMUST00000004971 VEGA | MGI Sequence Detail 2580 Not Applicable 
polypeptide OTTMUSP00000002395 VEGA | MGI Sequence Detail 743 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(60 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001664 Intermediate filament protein
InterPro IPR002957 Keratin, type I
Protein Ontology PR:000009503 keratin, type I cytoskeletal 9
References
(Earliest) J:51113 Powell BC, et al., The role of keratin proteins and their genes in the growth, structure and properties of hair. EXS. 1997;78:59-148
(Latest) J:206051 Fu DJ, et al., Keratin 9 is required for the structural integrity and terminal differentiation of the palmoplantar epidermis. J Invest Dermatol. 2014 Mar;134(3):754-63
All references(29)
Other
accession IDs
MGD-MRK-11651

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory