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Kcna7
Gene Detail
Symbol

Name
ID
Kcna7
potassium voltage-gated channel, shaker-related subfamily, member 7
MGI:96664
Synonyms
Kv1.7
Feature Type
protein coding gene
Genetic Map
Chromosome 7
29.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:45405960-45411382 bp, + strand
From NCBI annotation of GRCm38

  5423 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7791  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle

HCOP human homology predictions: KCNA7
Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcna7

Human
homologs
KCNA7, potassium channel, voltage gated shaker related subfamily A, member 7
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 3743
neXtProt AC: NX_Q96RP8

Human Synonyms: HAK6, KV1.7

Human Chr (Location): 19q13.3; chr19:49067418-49072941 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Kcna7 interacts with 158 markers (Mir10a, Mir10b, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component integral component of membrane, membrane, ...
Function delayed rectifier potassium channel activity, ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (5)    Tissues (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 5
cDNA source data(4)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) Genomic(1) cDNA(5) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000038201 (Evidence)
Entrez Gene 16495 (Evidence)
UniGene 12955
DFCI TC1589973
DoTS DT.40177582
NIA Mouse Gene Index U008072
Consensus CDS Project CCDS39951.1
International Mouse Phenotyping Consortium Status Kcna7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 16495 NCBI Gene Model | MGI Sequence Detail 5423 C57BL/6J ±  kb
transcript NM_010596 RefSeq | MGI Sequence Detail 3494 Not Specified 
polypeptide Q17ST2 UniProt | EBI | MGI Sequence Detail 489 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(73 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR005821 Ion transport domain
InterPro IPR003131 Potassium channel tetramerisation-type BTB domain
InterPro IPR003968 Potassium channel, voltage dependent, Kv
InterPro IPR003972 Potassium channel, voltage dependent, Kv1
InterPro IPR003091 Voltage-dependent potassium channel
InterPro IPR027359 Voltage-dependent potassium channel, four helix bundle domain
Protein Ontology PR:000000814 voltage-gated potassium channel subunit KCNA7
Graphical View of Protein Domain Structure
References
(Earliest) J:17629 Lock LF, et al., Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome. Genomics. 1994 Apr;20(3):354-62
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)
Other
accession IDs
MGD-MRK-11568

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory