Kcna7
Gene Detail

Symbol Name ID

Kcna7 potassium voltage-gated channel, shaker-related subfamily, member 7 MGI:96664

Synonyms

Kv1.7

Feature Type

protein coding gene

Genetic Map

Chromosome 7

29.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr7:45405960-45411382 bp, + strand From NCBI annotation of GRCm38   5423 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:7791  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcna7

Human homologs

Human Homolog		KCNA7, potassium voltage-gated channel, shaker-related subfamily, member 7
NCBI Gene ID		3743
neXtProt AC		NX_Q96RP8
Human Synonyms		HAK6, KV1.7
Human Chr (Location)		19q13.3; chr19:49570675-49576198 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (18 annotations)

Process	ion transport, potassium ion transmembrane transport, ...
Component	integral to membrane, membrane, ...
Function	delayed rectifier potassium channel activity, ion channel activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (5)    Tissues (4)   
Theiler Stages: 25, 28

Assay Type	Results
RT-PCR	5

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(7) Genomic(1) cDNA(5) Primer pair(1)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000038201 (Evidence)
Entrez Gene	16495 (Evidence)
UniGene	12955
DFCI	TC1589973
DoTS	DT.40177582
NIA Mouse Gene Index	U008072
Consensus CDS Project	CCDS39951.1
International Mouse Knockout Project Status	Kcna7

Sequences

Length	Strain/Species
genomic	16495	NCBI Gene Model | MGI Sequence Detail	5423	C57BL/6J
transcript	NM_010596	RefSeq | MGI Sequence Detail	3494	Not Specified
polypeptide	Q17ST2	UniProt | EBI | MGI Sequence Detail	489	Not Applicable

All sequences(20) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(69 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011333	BTB/POZ fold
InterPro	IPR000210	BTB/POZ-like
InterPro	IPR005821	Ion transport domain
InterPro	IPR003131	Potassium channel tetramerisation-type BTB domain
InterPro	IPR003968	Potassium channel, voltage dependent, Kv
InterPro	IPR003972	Potassium channel, voltage dependent, Kv1
InterPro	IPR003091	Voltage-dependent potassium channel
Protein Ontology	PR:000000814	voltage-gated potassium channel subunit KCNA7

Graphical View of Protein Domain Structure

References

(Earliest) J:23841 McPherson JD, et al., Chromosomal localization of 7 potassium channel genes. Cytogenet Cell Genet. 1991;58:1979 (Abstr.)
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Other accession IDs

MGD-MRK-11568