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Kcna7 Gene Detail
Summary
  • Symbol
    Kcna7
  • Name
    potassium voltage-gated channel, shaker-related subfamily, member 7
  • Synonyms
    Kv1.7
  • Feature Type
    protein coding gene
  • IDs
    MGI:96664
    NCBI Gene: 16495
Location & Maps
more
  • Sequence Map
    Chr7:45405960-45411382 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5423 bp   ±  kb flank

  • Genome Browsers
Homology
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  • Human Ortholog
    KCNA7, potassium channel, voltage gated shaker related subfamily A, member 7
  • Vertebrate Orthologs
    5
  • Human Ortholog
    KCNA7, potassium channel, voltage gated shaker related subfamily A, member 7
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HAK6, KV1.7
  • Links
    NCBI Gene ID: 3743
    neXtProt AC: NX_Q96RP8

  • Chr Location
    19q13.3; chr19:49067418-49072941 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 16495 NCBI Gene Model | MGI Sequence Detail 5423 C57BL/6J ±  kb
transcript NM_010596 RefSeq | MGI Sequence Detail 3494 Not Specified  
polypeptide Q17ST2 UniProt | EBI | MGI Sequence Detail 489 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    73 from dbSNP Build 137
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000000814 voltage-gated potassium channel subunit KCNA7
  • InterPro Domains
    IPR000210 BTB/POZ domain
    IPR005821 Ion transport domain
    IPR003131 Potassium channel tetramerisation-type BTB domain
    IPR003968 Potassium channel, voltage dependent, Kv
    IPR003972 Potassium channel, voltage dependent, Kv1
    IPR011333 SKP1/BTB/POZ domain
    IPR027359 Voltage-dependent channel, four helix bundle domain
    IPR028325 Voltage-gated potassium channel
Molecular
Reagents
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  • All nucleic 7
    Genomic 1
    cDNA 5
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-11568
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:17629 Lock LF, et al., Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome. Genomics. 1994 Apr;20(3):354-62
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory