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Ina Gene Detail
Summary
  • Symbol
    Ina
  • Name
    internexin neuronal intermediate filament protein, alpha
  • Synonyms
    MGC:25352, NF66, NF-66
  • Feature Type
    protein coding gene
  • IDs
    MGI:96568
    NCBI Gene: 226180
Location & Maps
more
  • Sequence Map
    Chr19:47014698-47025327 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10630 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 39.07 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    INA, internexin neuronal intermediate filament protein alpha
  • Vertebrate Orthologs
    8
  • Human Ortholog
    INA, internexin neuronal intermediate filament protein alpha
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NEF5, NF-66, TXBP-1
  • Links
    NCBI Gene ID: 9118
    neXtProt AC: NX_Q16352

  • Chr Location
    10q24.33; chr10:103277163-103290351 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 10433
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: INA
  • Gene Tree
    Ina
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    8 phenotype references
Homozygous mice are healthy and viable, and do not exhibit any obvious abnormalities; no defects in the nervous system were detected, including brain development, axon outgrowth, or guidance.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016340 VEGA Gene Model | MGI Sequence Detail 10630 C57BL/6J ±  kb
transcript OTTMUST00000039267 VEGA | MGI Sequence Detail 3240 Not Applicable  
polypeptide OTTMUSP00000017549 VEGA | MGI Sequence Detail 501 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    160 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    Genomic 1
    cDNA 5
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-11403, MGI:2147669
References
more
  • Summaries
    All 48
    Developmental Gene Expression 13
    Gene Ontology 9
    Phenotypes 8
  • Earliest
    J:11497 Ching GY, et al., Structure of the gene for the neuronal intermediate filament protein alpha-internexin and functional analysis of its promoter. J Biol Chem. 1991 Oct 15;266(29):19459-68
  • Latest
    J:220735 Wu F, et al., Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1559-68

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory