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Il9r Gene Detail
Summary
  • Symbol
    Il9r
  • Name
    interleukin 9 receptor
  • Feature Type
    protein coding gene
  • IDs
    MGI:96564
    NCBI Gene: 16199
  • Gene Overview
    MyGene.info: IL9R
Location & Maps
more
  • Sequence Map
    Chr11:32187541-32200279 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12739 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    IL9R, interleukin 9 receptor
  • Vertebrate Orthologs
    7
  • Human Ortholog
    IL9R, interleukin 9 receptor
    Orthology source: HomoloGene
  • Synonyms
    CD129, IL-9R
  • Links
    NCBI Gene ID: 3581
    neXtProt AC: NX_Q01113

  • Chr Location
    XYq28 and Yq12

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Il9r
  • Incidental Mutations
Homozygous null mice are more susceptible to experimental autoimmune encephalomyelitis, a defect partially attributable to defective regulatory T cell function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006344 VEGA Gene Model | MGI Sequence Detail 12739 C57BL/6J ±  kb
transcript OTTMUST00000083374 VEGA | MGI Sequence Detail 1542 Not Applicable  
polypeptide OTTMUSP00000044790 VEGA | MGI Sequence Detail 474 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    248 from dbSNP Build 142
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000001397 interleukin-9 receptor
  • InterPro Domains
    IPR003961 Fibronectin type III
    IPR013783 Immunoglobulin-like fold
    IPR003531 Short hematopoietin receptor, family 1, conserved site
Molecular
Reagents
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  • All nucleic 13
    Genomic 1
    cDNA 11
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-11398
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 15
  • Earliest
    J:1236 Renauld JC, et al., Expression cloning of the murine and human interleukin 9 receptor cDNAs. Proc Natl Acad Sci U S A. 1992 Jun 15;89(12):5690-4
  • Latest
    J:192672 Purwar R, et al., Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat Med. 2012 Jul 8;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory