Igkc
Gene Detail

Symbol Name ID

Igkc immunoglobulin kappa constant MGI:96495

Feature Type

gene segment

Genetic Map

Chromosome 6

32.04 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(17)

Sequence Map

Chr6:70726435-70726754 bp, + strand From NCBI annotation of GRCm38   320 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

Gene Tree: Igkc

Alleles and phenotypes

All alleles(6) : Targeted(6)

Gene Ontology (GO) classifications

All GO classifications: (1 annotations)

Process

B cell differentiation

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (58)    Tissues (48)    Images (1)
Theiler Stages: 10, 18, 23, 25, 28

Assay Type	Results
Northern blot	12
RT-PCR	46

cDNA source data(5)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(99) Genomic(61) cDNA(32) Primer pair(3) Other(3)
Microarray probesets(1)

Other database links

Ensembl Gene Model	ENSMUSG00000076609 (Evidence)
Entrez Gene	16071 (Evidence)
PDB	1ZEA, 2A1W, 2DTM, 2OJZ, 3EYS, 3EYU, 3UYR, 3V4U, 2OK0, 3UO1, 3V52
International Mouse Knockout Project Status	Igkc

Sequences

Length	Strain/Species
genomic	16071	NCBI Gene Model | MGI Sequence Detail	320	C57BL/6J
transcript	BC110685	GenBank | EMBL | DDBJ | MGI Sequence Detail	1017	CZECHII
polypeptide	A2NHM3	UniProt | EBI | MGI Sequence Detail	219	Not Applicable

All sequences(14) RefSeq(1) UniProt(2)

Polymorphisms

All PCR and RFLP(5) : PCR(1) RFLP(4) SNPs(0 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003597	Immunoglobulin C1-set
InterPro	IPR007110	Immunoglobulin-like
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003006	Immunoglobulin/major histocompatibility complex, conserved site
InterPro	IPR013106	Immunoglobulin V-set
InterPro	IPR003596	Immunoglobulin V-set, subgroup
Protein Ontology	PR:000008966	Ig kappa chain C region

References

(Earliest) J:6069 Seidman JG, et al., The arrangement and rearrangement of antibody genes. Nature. 1978 Dec 21-28;276(5690):790-5
(Latest) J:194594 Andrews SF, et al., Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity. J Exp Med. 2013 Jan 14;210(1):125-42
All references(98)

Other accession IDs

MGD-MRK-11293