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Igkc
Gene Detail
Symbol

Name
ID
Igkc
immunoglobulin kappa constant
MGI:96495
Feature Type
gene segment
Genetic Map
Chromosome 6
32.04 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(17)
Sequence Map
Chr6:70726435-70726754 bp, + strand
From NCBI annotation of GRCm38

  320 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
Gene Tree: Igkc
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Gene Ontology
(GO)
classifications
All GO classifications: (2 annotations)
Process B cell differentiation
Function metal ion binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (58)    Tissues (48)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 12
RT-PCR 46
cDNA source data(5)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(99) Genomic(61) cDNA(32) Primer pair(3) Other(3)
Microarray probesets(1)
Other database
links
Ensembl Gene ModelENSMUSG00000076609 (Evidence)
Entrez Gene16071 (Evidence)
PDB1CBV, 1CGS, 1F3D, 1M7D, 1M7I, 1MNU, 1MPA, 1NBV, 1PLG, 1QFU, 1T2Q, 1YNK, 1YNL, 1ZEA, 2A1W, 2CGR, 2DQT, 2DQU, 2DTM, 2IPT, 2IPU, 2IQA, 2MPA, 2OJZ, 2R0W, 2R0Z, 3BAE, 3BKC, 3BKJ, 3BKM, 3BQU, 3EYS, 3EYU, 3UYR, 3V4U, 4HDI, 1LO0, 1M71, 1PZ5, 2IQ9, 2OK0, 3UO1, 3V52, 4F37
International Mouse Knockout Project StatusIgkc
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 16071 NCBI Gene Model | MGI Sequence Detail 320 C57BL/6J ±  kb
transcript BC110685 GenBank | EMBL | DDBJ | MGI Sequence Detail 1017 CZECHII 
polypeptide A2NHM3 UniProt | EBI | MGI Sequence Detail 219 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(1) UniProt(4)
Polymorphisms
All PCR and RFLP(5) : PCR(1) RFLP(4) SNPs within 2kb(65 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003597 Immunoglobulin C1-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
InterPro IPR013106 Immunoglobulin V-set
InterPro IPR003596 Immunoglobulin V-set, subgroup
Protein Ontology PR:000008966 Ig kappa chain C region
References
(Earliest) J:6069 Seidman JG, et al., The arrangement and rearrangement of antibody genes. Nature. 1978 Dec 21-28;276(5690):790-5
(Latest) J:205764 Doyle-Cooper C, et al., Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10. J Immunol. 2013 Sep 15;191(6):3186-91
All references(100)
Other
accession IDs
MGD-MRK-11293

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory