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Ighg1
Gene Detail
 Symbol
Name
ID
Ighg1
immunoglobulin heavy constant gamma 1 (G1m marker)
MGI:96446
Synonyms IgG1, Igh-4
Feature Type gene segment
Genetic Map
Chromosome 12
62.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:113328976-113330523 bp, - strand
From Ensembl annotation of GRCm38

  1548 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
Gene Tree: Ighg1
Alleles
and
phenotypes
All alleles(8) : Targeted(8)
 
Mutant mice are viable and fertile but show impaired primary and secondary Igh-4 immune responses.
 
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process antibacterial humoral response, antibody-dependent cellular cytotoxicity, ...
Component external side of plasma membrane, extracellular space, ...
Function antigen binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(4)
External Resources: GEO   ArrayExpress
Molecular
reagents
All nucleic(34) Genomic(20) cDNA(12) Other(2)
Microarray probesets(1)
Other database
links
Ensembl Gene ModelENSMUSG00000076614 (Evidence)
Entrez Gene16017 (Evidence)
International Mouse Knockout Project StatusIghg1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000076614 Ensembl Gene Model | MGI Sequence Detail 1548 C57BL/6J ±  kb
transcript ENSMUST00000103420 Ensembl | MGI Sequence Detail 974 Not Applicable 
polypeptide ENSMUSP00000100216 Ensembl | MGI Sequence Detail 324 Not Applicable 

For the selected sequences
All sequences(15) RefSeq(1)
Polymorphisms RFLP(3) : SNPs within 2kb(103 from dbSNP Build 137)
References (Earliest) J:5041 Minna JD, et al., Identification of a gene locus for gamma-G-1 immunoglobulin H chains and its linkage to the H chain chromosome region in the mouse. Proc Natl Acad Sci U S A. 1967 Jul;58(1):188-94
(Latest) J:209879 Ulusoy C, et al., Preferential production of IgG1, IL-4 and IL-10 in MuSK-immunized mice. Clin Immunol. 2014 Apr;151(2):155-63
All references(99)
Other
accession IDs
MGD-MRK-11243

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory