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Ighg1
Gene Detail
Symbol

Name
ID
Ighg1
immunoglobulin heavy constant gamma 1 (G1m marker)
MGI:96446
Synonyms
IgG1, Igh-4
Feature Type
gene segment
Genetic Map
Chromosome 12
62.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:113325240-113330523 bp, - strand
From VEGA annotation of GRCm38

  5284 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Ighg1
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Targeted(8) Transgenic(1)
 
Mutant mice are viable and fertile but show impaired primary and secondary Igh-4 immune responses.
 
Mutations Annotated to Human Diseases (1)   
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process antibacterial humoral response, antibody-dependent cellular cytotoxicity, ...
Component external side of plasma membrane, extracellular space, ...
Function antigen binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(4)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(34) Genomic(20) cDNA(12) Other(2)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000051474 (Evidence)
Ensembl Gene ModelENSMUSG00000076614 (Evidence)
Entrez Gene16017 (Evidence)
International Mouse Knockout Project StatusIghg1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051474 VEGA Gene Model | MGI Sequence Detail 5284 C57BL/6J ±  kb
transcript OTTMUST00000130065 VEGA | MGI Sequence Detail 2482 Not Applicable 
polypeptide OTTMUSP00000069779 VEGA | MGI Sequence Detail 393 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(1) UniProt(2)
Polymorphisms
RFLP(3) : SNPs within 2kb(177 from dbSNP Build 137)    SNPs within 2kb including multiple locations(181)
Protein-related
information
ResourceIDDescription
InterPro IPR003597 Immunoglobulin C1-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
References
(Earliest) J:5041 Minna JD, et al., Identification of a gene locus for gamma-G-1 immunoglobulin H chains and its linkage to the H chain chromosome region in the mouse. Proc Natl Acad Sci U S A. 1967 Jul;58(1):188-94
(Latest) J:209879 Ulusoy C, et al., Preferential production of IgG1, IL-4 and IL-10 in MuSK-immunized mice. Clin Immunol. 2014 Apr;151(2):155-63
All references(101)
Other
accession IDs
MGD-MRK-11243

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/17/2015
MGI 5.21
The Jackson Laboratory