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Igh Complex/Cluster/Region Detail
Summary
  • Symbol
    Igh
  • Name
    immunoglobulin heavy chain complex
Location & Maps
more
  • Sequence Map
    Chr12:113258768-116009954 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2751187 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, Syntenic
  • Mapping Data
    26 experiments
Human Diseases
more
  • Diseases
    1 with Igh mouse models

Human Disease Mouse Models
      
IDs
View 3 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    6 with disease annotations
  • References
    7 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    107 phenotypes from 66 alleles in 40 genetic backgrounds
    95 phenotypes from multigenic genotypes
    332 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit abnormal B cell morphology and physiology.
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 111507 NCBI Gene Model | MGI Sequence Detail 2751187 C57BL/6J ±  kb
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    43670 from dbSNP Build 142
  • PCR
  • RFLP
Molecular
Reagents
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  • All nucleic 11
    Genomic 2
    cDNA 2
    Primer pair 6
    Other 1
Other
Accession IDs
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MGD-MRK-11239
References
more
  • Summaries
    All 453
    Diseases 7
    Phenotypes 332
  • Earliest
    J:5559 Taylor BA, et al., Genes for immunoglobulin heavy chain and serum prealbumin protein are linked in mouse. Nature. 1975 Aug 21;256(5519):644-6
  • Latest
    J:239451 Yang Z, et al., Regulation of B cell fate by chronic activity of the IgE B cell receptor. Elife. 2016 Dec 09;5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/23/2017
MGI 6.09
The Jackson Laboratory