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Igh
Complex/Cluster/Region Detail
 Symbol
Name
ID
Igh
immunoglobulin heavy chain complex
MGI:96442
Feature Type complex/cluster/region
Genetic Map
Chromosome 12
Syntenic

Mapping data(25)
Mutations,
alleles, and
phenotypes
All mutations/alleles(73) : Targeted(73)
 
Mice homozygous for a knock-out allele exhibit abnormal B cell morphology and physiology.
 
Human Diseases Modeled Using Mouse Igh (1)    Alleles Annotated to Human Diseases(2)   
Molecular
reagents
All nucleic(11) Genomic(2) cDNA(2) Primer pair(6) Other(1)
Other database
links
Entrez Gene111507 (Evidence)
Sequences
Representative SequencesLengthStrain/SpeciesFlank

For the selected sequences
All sequences(1) RefSeq(1)
Polymorphisms All PCR and RFLP(14) : PCR(10) RFLP(4) SNPs within 2kb(0 from dbSNP Build 137)
References (Earliest) J:5559 Taylor BA, et al., Genes for immunoglobulin heavy chain and serum prealbumin protein are linked in mouse. Nature. 1975 Aug 21;256(5519):644-6
(Latest) J:212178 Teodorovic LS, et al., Activation of Ras overcomes B-cell tolerance to promote differentiation of autoreactive B cells and production of autoantibodies. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):E2797-806
All references(307)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-11239

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory