Rr152 Other Genome Feature Detail

Summary

• Symbol
  Rr152
• Name
  regulatory region 152
• Synonyms
  3'RR

• Feature Type
  enhancer
• IDs
  MGI:6858039
• Cluster Members
  Rr156, Rr155, Rr153 ... (4 members)
• Regulates expression of
  Igh (1 regulated gene)

Location &
Maps

• Sequence Map
  Chr12:113191890-113217660 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 12, Syntenic

Strain
Comparison

• SNPs within 2kb
  667 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  14 phenotypes from 4 alleles in 3 genetic backgrounds
  29 phenotype references
  

• All Mutations and Alleles
  8
• Endonuclease-mediated
  1
• Targeted
  7
• Find Mice (IMSR)
  6 strains or lines available

References

• Summaries
  All 30

  Phenotypes 29
• Earliest
  J:71300 Pinaud E, et al., Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination. Immunity. 2001 Aug;15(2):187-99
• Latest
  J:359652 Bruzeau C, et al., Core enhancers of the 3'RR optimize IgH nuclear position and loop conformation for successful oriented class switch recombination. Nucleic Acids Res. 2024 Nov 11;52(20):12281-12294

Rr152 regulates expression of:

Feature	Feature Type	Location	Reference
Igh, immunoglobulin heavy chain complex	complex/cluster/region	Chr12:113222388-115973574 (-)	J:234741

Rr152 Cluster contains:

More Data for these features

Member	Feature Type	Location
Rr156, regulatory region 156	enhancer	Chr12:113191890-113191986
Rr155, regulatory region 155	enhancer	Chr12:113195964-113196046
Rr153, regulatory region 153	enhancer	Chr12:113208282-113208364
Rr154, regulatory region 154	enhancer	Chr12:113217466-113217660