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Cd79b
Gene Detail
 Symbol
Name
ID
Cd79b
CD79B antigen
MGI:96431
Synonyms B29, Igb, Igbeta, Ig-beta
Feature Type protein coding gene
Genetic Map
Chromosome 11
68.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:106311341-106314762 bp, - strand
From VEGA annotation of GRCm38

  3422 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:521  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Cd79b

Human
homologs
Human Homolog CD79B, CD79b molecule, immunoglobulin-associated beta
NCBI Gene ID 974
neXtProt AC  NX_P40259
Human Synonyms  AGM6, B29, IGB
Human Chr (Location)  17q23; chr17:63928738-63932349 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CD79B
Alleles
and
phenotypes
All alleles(13) : Gene trapped(2) Spontaneous(1) Targeted(10)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for targeted null mutations exhibit arrested development of B cells at the pro-B cell stage due to diminished signaling of the B cell receptor.
 
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process B cell receptor signaling pathway, cell surface receptor signaling pathway, ...
Component B cell receptor complex, cytoplasm, ...
Function protein binding, transmembrane signaling receptor activity
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (55)    Tissues (47)    Images (1)
Theiler Stages: 22, 23, 28
Assay TypeResults
RT-PCR 55
cDNA source data(33)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(38) Genomic(1) cDNA(33) Primer pair(4)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000003415 (Evidence)
Ensembl Gene ModelENSMUSG00000040592 (Evidence)
Entrez Gene15985 (Evidence)
UniGene2987
DFCITC1581283
DoTSDT.529403
NIA Mouse Gene IndexU033541
PDB3KHO, 3KHQ
Consensus CDS ProjectCCDS48960.1
International Mouse Knockout Project StatusCd79b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003415 VEGA Gene Model | MGI Sequence Detail 3422 C57BL/6J ±  kb
transcript OTTMUST00000007187 VEGA | MGI Sequence Detail 1431 Not Applicable 
polypeptide OTTMUSP00000003448 VEGA | MGI Sequence Detail 288 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(40 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR013106 Immunoglobulin V-set
InterPro IPR003110 Phosphorylated immunoreceptor signaling ITAM
Protein Ontology PR:000001286 B-cell antigen receptor complex-associated protein beta chain
References (Earliest) J:17556 Hermanson GG, et al., B29: a member of the immunoglobulin gene superfamily exclusively expressed on beta-lineage cells. Proc Natl Acad Sci U S A. 1988 Sep;85(18):6890-4
(Latest) J:179254 Patterson HC, et al., Cytoplasmic Ig alpha serine/threonines fine-tune Ig alpha tyrosine phosphorylation and limit bone marrow plasma cell formation. J Immunol. 2011 Sep 15;187(6):2853-8
All references(63)
Other
accession IDs
MGD-MRK-11225

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory