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Htr5b Gene Detail
Summary
  • Symbol
    Htr5b
  • Name
    5-hydroxytryptamine (serotonin) receptor 5B
Location &
Maps
more
  • Sequence Map
    Chr1:121437571-121456194 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 52.98 cM, cytoband E4-G
  • Mapping Data
    14 experiments
Strain
Comparison
more
  • SNPs within 2kb
    620 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96284
 protein coding gene Chr1:121437487-121458351 (-)
129S1/SvImJ ENSMUSG00200001755
 protein coding gene Chr1:118897649-118916401 (-)
A/J ENSMUSG00195004158
 protein coding gene Chr1:118138412-118157165 (-)
AKR/J ENSMUSG00220024728
 protein coding gene Chr1:117954259-117973013 (-)
BALB/cJ ENSMUSG00180012524
 protein coding gene Chr1:118565048-118583931 (-)
C3H/HeJ ENSMUSG00175018594
 protein coding gene Chr1:118369294-118388039 (-)
C57BL/6NJ ENSMUSG00215008573
 protein coding gene Chr1:118353922-118372665 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014528
 protein coding gene Chr1:113504711-113521238 (-)
CAST/EiJ ENSTCUG00005005866
 protein coding gene Chr1:117299439-117319261 (-)
CBA/J ENSMUSG00210001050
 protein coding gene Chr1:118198656-118217405 (-)
DBA/2J ENSMUSG00185001791
 protein coding gene Chr1:122642799-122661545 (-)
FVB/NJ ENSMUSG00205010504
 protein coding gene Chr1:117705063-117723816 (-)
JF1/MsJ ENSUMUG00000001323
 protein coding gene Chr1:121747555-121765203 (-)
LP/J ENSMUSG00230007190
 protein coding gene Chr1:122075309-122094053 (-)
NOD/ShiLtJ ENSMUSG00190006324
 protein coding gene Chr1:118183972-118202721 (-)
NZO/HlLtJ ENSMUSG00225004329
 protein coding gene Chr1:125880475-125899180 (-)
PWK/PhJ ENSLUMG00010014540
 protein coding gene Chr1:117361218-117378725 (-)
SPRET/EiJ ENSMSPG00010016585
 protein coding gene Chr1:120009808-120026901 (-)
WSB/EiJ ENSIUOG00005002927
 protein coding gene Chr1:118068850-118087743 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    17 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    3 involving Htr5b
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    20 strains or lines available
Mice homozygous for disruptions in this gene display a normal phenotype
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    691
  • Tissues
    72
  • cDNA Data
    6
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050534 Ensembl Gene Model | MGI Sequence Detail 18624 C57BL/6J ±  kb
transcript ENSMUST00000055884 Ensembl | MGI Sequence Detail 1935 Not Applicable  
polypeptide ENSMUSP00000057212 Ensembl | MGI Sequence Detail 370 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    Genomic 1
    cDNA 7
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-11012
References
more
  • Summaries
    All 57
    Developmental Gene Expression 6
    Gene Ontology 7
    Phenotypes 17
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:347117 Katada Y, et al., Starburst amacrine cells amplify optogenetic visual restoration through gap junctions. Mol Ther Methods Clin Dev. 2023 Sep 14;30:1-13
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory