About   Help   FAQ
Htr5b Gene Detail
Summary
  • Symbol
    Htr5b
  • Name
    5-hydroxytryptamine (serotonin) receptor 5B
  • Feature Type
    protein coding gene
  • IDs
    MGI:96284
    NCBI Gene: 15564
Location & Maps
more
  • Sequence Map
    Chr1:121509842-121528465 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      18624 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 52.98 cM, cytoband E4-G
  • Mapping Data
    14 experiments
Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Htr5b
  • Incidental Mutations
Mice homozygous for disruptions in this gene display a normal phenotype
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021025 VEGA Gene Model | MGI Sequence Detail 18624 C57BL/6J ±  kb
transcript OTTMUST00000049715 VEGA | MGI Sequence Detail 1935 Not Applicable  
polypeptide OTTMUSP00000023087 VEGA | MGI Sequence Detail 370 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    184 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000001170 5-hydroxytryptamine receptor 5B
  • InterPro Domains
    IPR000431 5-Hydroxytryptamine 5B receptor
    IPR002231 5-hydroxytryptamine receptor family
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
Molecular
Reagents
less
  • All nucleic 8
    Genomic 1
    cDNA 6
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-11012
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:15791 Matthes H, et al., Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization. Mol Pharmacol. 1993 Mar;43(3):313-9
  • Latest
    J:229195 Takata N, et al., Optogenetic activation of CA1 pyramidal neurons at the dorsal and ventral hippocampus evokes distinct brain-wide responses revealed by mouse fMRI. PLoS One. 2015;10(3):e0121417

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory