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Trmt2a Gene Detail
Summary
  • Symbol
    Trmt2a
  • Name
    TRM2 tRNA methyltransferase 2A
  • Synonyms
    Htf9c
  • Feature Type
    protein coding gene
  • IDs
    MGI:96270
    NCBI Gene: 15547
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:18248847-18254772 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 11.31 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96270
protein coding gene Chr16:18248679-18254772 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022606
protein coding gene Chr16:15455943-15462036 (+)
A/J MGP_AJ_G0022567
protein coding gene Chr16:14692527-14698620 (+)
AKR/J MGP_AKRJ_G0022544
protein coding gene Chr16:15270572-15276665 (+)
BALB/cJ MGP_BALBcJ_G0022572
protein coding gene Chr16:14841888-14847981 (+)
C3H/HeJ MGP_C3HHeJ_G0022339
protein coding gene Chr16:15434220-15440313 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023021
protein coding gene Chr16:15726132-15732225 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020541
protein coding gene Chr16:14743440-14749498 (+)
CAST/EiJ MGP_CASTEiJ_G0021866
protein coding gene Chr16:15322750-15328843 (+)
CBA/J MGP_CBAJ_G0022308
protein coding gene Chr16:16412047-16418140 (+)
DBA/2J MGP_DBA2J_G0022440
protein coding gene Chr16:14603922-14610015 (+)
FVB/NJ MGP_FVBNJ_G0022415
protein coding gene Chr16:14661245-14667338 (+)
LP/J MGP_LPJ_G0022507
protein coding gene Chr16:15239807-15245900 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022437
protein coding gene Chr16:16063643-16069736 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023032
protein coding gene Chr16:15207642-15213735 (+)
PWK/PhJ MGP_PWKPhJ_G0021608
protein coding gene Chr16:14874482-14880561 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021436
protein coding gene Chr16:15176337-15182383 (+)
WSB/EiJ MGP_WSBEiJ_G0021912
protein coding gene Chr16:15190845-15196939 (+)



Homology
more
  • Human Ortholog
    TRMT2A, tRNA methyltransferase 2 homolog A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TRMT2A, tRNA methyltransferase 2 homolog A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HTF9C
  • Links
    NCBI Gene ID: 27037
    neXtProt AC: NX_Q8IZ69
    UniProt: Q8IZ69

  • Chr Location
    22q11.21; chr22:20111866-20117305 (-)  GRCh38.p7

Human Diseases
less
  • References
    5 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    79 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 15547 NCBI Gene Model | MGI Sequence Detail 5926 C57BL/6J ±  kb
transcript NM_001081000 RefSeq | MGI Sequence Detail 3684 C57BL/6  
polypeptide Q8BNV1 UniProt | EBI | MGI Sequence Detail 574 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    Genomic 15
    cDNA 31
    Primer pair 2
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-10995
References
more
  • Summaries
    All 114
    Developmental Gene Expression 7
    Diseases 5
    Gene Ontology 2
    Phenotypes 79
  • Earliest
    J:17925 Bird A, et al., A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA. Cell. 1985 Jan;40(1):91-9
  • Latest
    J:289143 Welby L, et al., Persistent Feeding and Swallowing Deficits in a Mouse Model of 22q11.2 Deletion Syndrome. Front Neurol. 2020;11:4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
01/05/2021
MGI 6.16
The Jackson Laboratory