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Ranbp1 Gene Detail
Summary
  • Symbol
    Ranbp1
  • Name
    RAN binding protein 1
  • Synonyms
    Htf9a
  • Feature Type
    protein coding gene
  • IDs
    MGI:96269
    NCBI Gene: 19385
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:18057843-18066558 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 11.30 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96269
protein coding gene Chr16:18057648-18066596 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022605
protein coding gene Chr16:15447047-15455910 (-)
A/J MGP_AJ_G0022566
protein coding gene Chr16:14683631-14692494 (-)
AKR/J MGP_AKRJ_G0022543
protein coding gene Chr16:15260075-15270583 (-)
BALB/cJ MGP_BALBcJ_G0022571
protein coding gene Chr16:14832992-14841903 (-)
C3H/HeJ MGP_C3HHeJ_G0022338
protein coding gene Chr16:15425324-15434187 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023020
protein coding gene Chr16:15715617-15726099 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020540
protein coding gene Chr16:14734397-14743493 (-)
CAST/EiJ MGP_CASTEiJ_G0021865
protein coding gene Chr16:15312503-15322803 (-)
CBA/J MGP_CBAJ_G0022307
protein coding gene Chr16:16403151-16412060 (-)
DBA/2J MGP_DBA2J_G0022439
protein coding gene Chr16:14595032-14603934 (-)
FVB/NJ MGP_FVBNJ_G0022414
protein coding gene Chr16:14652213-14661212 (-)
LP/J MGP_LPJ_G0022506
protein coding gene Chr16:15230911-15239774 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022436
protein coding gene Chr16:16054750-16063610 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023031
protein coding gene Chr16:15198747-15207654 (-)
PWK/PhJ MGP_PWKPhJ_G0021607
protein coding gene Chr16:14865459-14874497 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021435
protein coding gene Chr16:15165971-15176390 (-)
WSB/EiJ MGP_WSBEiJ_G0021911
protein coding gene Chr16:15181942-15190857 (-)



Homology
more
  • Human Ortholog
    RANBP1, RAN binding protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RANBP1, RAN binding protein 1
  • Synonyms
    HTF9A
  • Links
    NCBI Gene ID: 5902
    neXtProt AC: NX_P43487
    UniProt: P43487

  • Chr Location
    22q11.21; chr22:20115938-20127355 (+)  GRCh38

Human Diseases
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  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    39 phenotypes from 3 alleles in 3 genetic backgrounds
    112 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit postnatal growth retardation, decreased body weight, impaired spermatogenesis, and male infertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic 19385 NCBI Gene Model | MGI Sequence Detail 8716 C57BL/6J ±  kb
    transcript NM_011239 RefSeq | MGI Sequence Detail 852 ZRU/MplStud  
    polypeptide P34022 UniProt | EBI | MGI Sequence Detail 203 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 87
      Genomic 14
      cDNA 71
      Primer pair 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-10994
    References
    more
    • Summaries
      All 154
      Developmental Gene Expression 12
      Diseases 6
      Gene Ontology 5
      Phenotypes 112
    • Earliest
      J:17925 Bird A, et al., A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA. Cell. 1985 Jan;40(1):91-9
    • Latest
      J:342597 Rummell BP, et al., Altered corollary discharge signaling in the auditory cortex of a mouse model of schizophrenia predisposition. Nat Commun. 2023 Nov 15;14(1):7388

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory