Ranbp1
Gene Detail

Symbol Name ID

Ranbp1 RAN binding protein 1 MGI:96269

Synonyms

Htf9a

Feature Type

protein coding gene

Genetic Map

Chromosome 16

11.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)

Sequence Map

Chr16:18239784-18248732 bp, - strand From VEGA annotation of GRCm38   8949 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:21600  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ran-specific GTPase-activating protein
Gene Tree: Ranbp1

Human homologs

Human Homolog		RANBP1, RAN binding protein 1
NCBI Gene ID		5902
neXtProt AC		NX_P43487
Human Synonyms		HTF9A
Human Chr (Location)		22q11.21; chr22:20105024-20114704 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(171) : Targeted(3) Gene trapped(168)
 

Mice homozygous for a knock-out allele exhibit postnatal growth retardation, decreased body weight, impaired spermatogenesis, and male infertility.

 

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	intracellular transport, positive regulation of mitotic centrosome separation, ...
Component	centrosome, cytoplasm
Function	GTPase activator activity

External Resources: FuncBase

Expression

Literature Summary: (8 records)
Data Summary: Results (107)    Tissues (51)    Images (33)
Theiler Stages: 15, 16, 17, 20, 22, 23, 24, 26, 28

Assay Type	Results
Immunohistochemistry	18
RNA in situ	27
RT-PCR	62

cDNA source data(68)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(86) Genomic(14) cDNA(70) Primer pair(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000026021 (Evidence)
Ensembl Gene Model	ENSMUSG00000005732 (Evidence)
Entrez Gene	19385 (Evidence)
UniGene	235287
DFCI	TC1572819
NIA Mouse Gene Index	U036857
Consensus CDS Project	CCDS37280.1
International Mouse Knockout Project Status	Ranbp1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000026021	VEGA Gene Model | MGI Sequence Detail	8949	C57BL/6J
transcript	OTTMUST00000064217	VEGA | MGI Sequence Detail	1085	Not Applicable
polypeptide	OTTMUSP00000031864	VEGA | MGI Sequence Detail	203	Not Applicable

All sequences(37) RefSeq(2) UniProt(3)

Polymorphisms

RFLP(1) : SNPs(3 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011993	Pleckstrin homology-like domain
InterPro	IPR000156	Ran binding domain
Protein Ontology	PR:000013709	ran-specific GTPase-activating protein

References

(Earliest) J:17925 Bird A, et al., A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA. Cell. 1985 Jan;40(1):91-9
(Latest) J:191130 Maynard TM, et al., 22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development. Hum Mol Genet. 2013 Jan 15;22(2):300-12
All references(55)

Other accession IDs

MGD-MRK-10994