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Hspa9
Gene Detail
 Symbol
Name
ID
Hspa9
heat shock protein 9
MGI:96245
Synonyms C3H-specific antigen, CSA, GRP75, Hsc74, Hsp74, Hsp74a, Hspa9a, mortalin, mot-2, mthsp70, PBP74
Feature Type protein coding gene
Genetic Map
Chromosome 18
18.80 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr18:34937414-34954357 bp, - strand
From VEGA annotation of GRCm38

  16944 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:39452  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: chaperone HSP70
Gene Tree: Hspa9

Human
homologs
Human Homolog HSPA9, heat shock 70kDa protein 9 (mortalin)
NCBI Gene ID 3313
neXtProt AC  NX_P38646
Human Synonyms  CSA, GRP75, GRP-75, HEL-S-124m, HSPA9B, MOT, MOT2, MTHSP75, PBP74
Human Chr (Location)  5q31.1; chr5:138554882-138575629 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(58) : Gene trapped(56) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Hspa9 interacts with 171 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process protein export from nucleus, protein folding
Component cytoplasm, extracellular vesicular exosome, ...
Function ATP binding, enzyme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (26)    Tissues (14)    Images (1)
Theiler Stages: 1, 2, 3, 4, 28
Assay TypeResults
Immunohistochemistry 19
Western blot 2
RT-PCR 5
cDNA source data(360)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(372) Genomic(8) cDNA(362) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000037646 (Evidence)
Ensembl Gene ModelENSMUSG00000024359 (Evidence)
Entrez Gene15526 (Evidence)
UniGene209419
DFCITC1573799
DoTSDT.496548, DT.94413174
NIA Mouse Gene IndexU038317, U282218
Consensus CDS ProjectCCDS29138.1
International Mouse Knockout Project StatusHspa9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037646 VEGA Gene Model | MGI Sequence Detail 16944 C57BL/6J ±  kb
transcript OTTMUST00000097161 VEGA | MGI Sequence Detail 3049 Not Applicable 
polypeptide OTTMUSP00000054429 VEGA | MGI Sequence Detail 679 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(2) UniProt(1)
Polymorphisms All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(124 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012725 Chaperone DnaK
InterPro IPR018181 Heat shock protein 70, conserved site
InterPro IPR013126 Heat shock protein 70 family
Protein Ontology PR:000008813 stress-70 protein, mitochondrial
References (Earliest) J:116661 Kusakabe M, et al., A novel methodology for analysis of cell distribution in chimeric mouse organs using a strain specific antibody. J Cell Biol. 1988 Jul;107(1):257-65
(Latest) J:195331 Voloboueva LA, et al., Inflammatory response of microglial BV-2 cells includes a glycolytic shift and is modulated by mitochondrial glucose-regulated protein 75/mortalin. FEBS Lett. 2013 Mar 18;587(6):756-62
All references(63)
Other
accession IDs
MGD-MRK-10961, MGI:1345461

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory