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Hoxc5
Gene Detail
Symbol

Name
ID
Member of
Hoxc5
homeobox C5
MGI:96196
Hoxc cluster
Synonyms
Hox-3.4, Hox-6.2
Feature Type
protein coding gene
Genetic Map
Chromosome 15
58.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr15:102967443-103017429 bp, + strand
From VEGA annotation of GRCm38

  49987 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41296  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: homeotic protein Hox A5/D4
Gene Tree: Hoxc5

Human
homologs
Human Homolog HOXC5, homeobox C5
NCBI Gene ID 3222
neXtProt AC  NX_Q00444
Human Synonyms  CP11, HOX3, HOX3D
Human Chr (Location)  12q13.3; chr12:54016852-54035361 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Radiation induced(1) Targeted(3)
Genomic Mutations involving Hoxc5 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Hoxc5 interacts with 221 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process anterior/posterior pattern specification, embryonic skeletal system development, ...
Component cell junction, nucleoplasm, ...
Function DNA binding, sequence-specific DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (36 records)
Data Summary: Results (287)    Tissues (189)    Images (52)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 264
Northern blot 9
RT-PCR 13
RNase protection 1
cDNA source data(19)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(33) Genomic(8) cDNA(21) Primer pair(3) Other(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000037400 (Evidence)
Ensembl Gene ModelENSMUSG00000022485 (Evidence)
Entrez Gene15424 (Evidence)
UniGene103825
DFCITC1584514
DoTSDT.524988, DT.55247224
NIA Mouse Gene IndexU016735
Consensus CDS ProjectCCDS27896.1
International Mouse Knockout Project StatusHoxc5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037400 VEGA Gene Model | MGI Sequence Detail 49987 C57BL/6J ±  kb
transcript OTTMUST00000096505 VEGA | MGI Sequence Detail 2923 Not Applicable 
polypeptide OTTMUSP00000053931 VEGA | MGI Sequence Detail 222 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(107 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017970 Homeobox, conserved site
InterPro IPR017995 Homeobox protein, antennapedia type
InterPro IPR001827 Homeobox protein, antennapedia type, conserved site
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR020479 Homeodomain, metazoa
Protein Ontology PR:000008712 homeobox protein Hox-C5
References
(Earliest) J:9353 Sharpe PT, et al., Isolation and expression of a new mouse homeobox gene. Development. 1988 Feb;102(2):397-407
(Latest) J:211197 Nishimoto S, et al., A combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity. PLoS Genet. 2014 Mar;10(3):e1004245
All references(73)
Other
accession IDs
MGD-MRK-10842, MGD-MRK-10866, MGD-MRK-10897, MGI:2145954

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory