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Hoxc5 Gene Detail
Summary
  • Symbol
    Hoxc5
  • Name
    homeobox C5
  • Synonyms
    Hox-3.4, Hox-6.2
  • Feature Type
    protein coding gene
  • IDs
    MGI:96196
    NCBI Gene: 15424
  • Member of
    Hoxc cluster
  • Gene Overview
    MyGene.info: HOXC5
Location & Maps
more
  • Sequence Map
    Chr15:102967443-103017429 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      49987 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 58.07 cM
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    HOXC5, homeobox C5
  • Vertebrate Orthologs
    8
  • Human Ortholog
    HOXC5, homeobox C5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CP11, HOX3, HOX3D
  • Links
    NCBI Gene ID: 3222
    neXtProt AC: NX_Q00444

  • Chr Location
    12q13.3; chr12:54016852-54035361 (+)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotypes from multigenic genotypes
    27 phenotype references
  • All Mutations and Alleles
    6
  • Radiation induced
    2
  • Targeted
    4
  • Genomic Mutations
    3 involving Hoxc5
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037400 VEGA Gene Model | MGI Sequence Detail 49987 C57BL/6J ±  kb
transcript OTTMUST00000096505 VEGA | MGI Sequence Detail 2923 Not Applicable  
polypeptide OTTMUSP00000053931 VEGA | MGI Sequence Detail 222 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    107 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    Genomic 8
    cDNA 21
    Primer pair 3
    Other 1

    Microarray probesets 7
Other
Accession IDs
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MGD-MRK-10842, MGD-MRK-10866, MGD-MRK-10897, MGI:2145954
References
more
  • Summaries
    All 74
    Developmental Gene Expression 41
    Diseases 1
    Gene Ontology 4
    Phenotypes 27
  • Earliest
    J:9353 Sharpe PT, et al., Isolation and expression of a new mouse homeobox gene. Development. 1988 Feb;102(2):397-407
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory