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Hoxc5
Gene Detail
Symbol

Name
ID
Member of
Hoxc5
homeobox C5
MGI:96196
Hoxc cluster
Synonyms
Hox-3.4, Hox-6.2
Feature Type
protein coding gene
Genetic Map
Chromosome 15
58.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr15:102967443-103017429 bp, + strand
From VEGA annotation of GRCm38

  49987 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41296  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: HOXC5
Protein SuperFamily: homeotic protein Hox A5/D4
Gene Tree: Hoxc5

Human
homologs
HOXC5, homeobox C5
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 3222
neXtProt AC: NX_Q00444

Human Synonyms: CP11, HOX3, HOX3D

Human Chr (Location): 12q13.3; chr12:54016852-54035361 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Radiation induced(1) Targeted(3)
Genomic Mutations involving Hoxc5 (1)
Incidental mutations (data from Mutagenetix , APF )
Phenotype Images(2)
Interactions
Hoxc5 interacts with 221 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process anterior/posterior pattern specification, embryonic skeletal system development, ...
Component cell junction, nucleoplasm, ...
Function DNA binding, sequence-specific DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (37 records)
Data Summary: Results (287)    Tissues (189)    Images (52)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 264
Northern blot 9
RT-PCR 13
RNase protection 1
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase hoxc5 ; ZFIN hoxc5a    NEW 
Molecular
reagents
All nucleic(33) Genomic(8) cDNA(21) Primer pair(3) Other(1)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000037400 (Evidence)
Ensembl Gene Model ENSMUSG00000022485 (Evidence)
Entrez Gene 15424 (Evidence)
UniGene 103825
DFCI TC1584514
DoTS DT.524988, DT.55247224
NIA Mouse Gene Index U016735
Consensus CDS Project CCDS27896.1
International Mouse Phenotyping Consortium Status Hoxc5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037400 VEGA Gene Model | MGI Sequence Detail 49987 C57BL/6J ±  kb
transcript OTTMUST00000096505 VEGA | MGI Sequence Detail 2923 Not Applicable 
polypeptide OTTMUSP00000053931 VEGA | MGI Sequence Detail 222 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(107 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017970 Homeobox, conserved site
InterPro IPR017995 Homeobox protein, antennapedia type
InterPro IPR001827 Homeobox protein, antennapedia type, conserved site
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR020479 Homeodomain, metazoa
Protein Ontology PR:000008712 homeobox protein Hox-C5
References
(Earliest) J:9353 Sharpe PT, et al., Isolation and expression of a new mouse homeobox gene. Development. 1988 Feb;102(2):397-407
(Latest) J:221396 Sheikh BN, et al., MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5437-42
All references(73)
Other
accession IDs
MGD-MRK-10842, MGD-MRK-10866, MGD-MRK-10897, MGI:2145954

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory