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Hbb-y
Gene Detail
 Symbol
Name
ID
Hbb-y
hemoglobin Y, beta-like embryonic chain
MGI:96027
Synonyms epsilon Y globin, Ey, Hby
Feature Type protein coding gene
Genetic Map
Chromosome 7
54.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(11)
Sequence Map
Chr7:103851745-103853240 bp, - strand
From VEGA annotation of GRCm38

  1496 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:128032  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: globin
Gene Tree: Hbb-y

Human
homologs
Human Homolog HBG2, hemoglobin, gamma G
NCBI Gene ID 3048
neXtProt AC  NX_P69892
Human Synonyms  TNCY
Human Chr (Location)  11p15.5; chr11:5253191-5254781 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human HBG2
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
 
Mice with disruptions in this gene are grossly normal and viable through adulthood.
 
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process negative regulation of transcription from RNA polymerase II promoter, oxygen transport, ...
Component blood microparticle, hemoglobin complex
Function heme binding, hemoglobin alpha binding, ...
External Resources: FuncBase
Expression
Literature Summary: (68 records)
Data Summary: Results (146)    Tissues (68)    Images (14)
Theiler Stages: 10, 13, 15, 17, 18, 19, 20, 21, 22, 24, 28
Assay TypeResults
RNA in situ 48
Northern blot 10
RT-PCR 84
RNase protection 1
Nuclease S1 3
cDNA source data(596)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(633) Genomic(24) cDNA(596) Primer pair(11) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000019058 (Evidence)
Ensembl Gene ModelENSMUSG00000052187 (Evidence)
Entrez Gene15135 (Evidence)
UniGene440164
DFCITC1573884, TC1596936, TC1718481
DoTSDT.101409326, DT.40139051, DT.91537819, DT.94374029, DT.97416280
Consensus CDS ProjectCCDS21593.1
International Mouse Knockout Project StatusHbb-y
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019058 VEGA Gene Model | MGI Sequence Detail 1496 C57BL/6J ±  kb
transcript OTTMUST00000045676 VEGA | MGI Sequence Detail 661 Not Applicable 
polypeptide OTTMUSP00000020553 VEGA | MGI Sequence Detail 147 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(3)
Polymorphisms All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(99 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000971 Globin
InterPro IPR009050 Globin-like
InterPro IPR012292 Globin, structural domain
InterPro IPR002337 Haemoglobin, beta
Protein Ontology PR:000034323 hemoglobin subunit epsilon-Y2
References (Earliest) J:5065 Gilman JG, et al., Fetal hemoglobin variants in mice. Science. 1968 May 24;160(830):885-6
(Latest) J:186666 Pang CJ, et al., Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis. Mol Cell Biol. 2012 Jul;32(13):2628-44
All references(111)
Other
accession IDs
MGD-MRK-10639

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory