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Hbb-bh1 Gene Detail
Summary
  • Symbol
    Hbb-bh1
  • Name
    hemoglobin Z, beta-like embryonic chain
  • Synonyms
    betaH1, beta Hl globin
  • Feature Type
    protein coding gene
  • IDs
    MGI:96024
    NCBI Gene: 15132
  • Member of
    Hbb cluster
Location & Maps
more
  • Sequence Map
    Chr7:103841637-103843164 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1528 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 54.85 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    HBE1, hemoglobin subunit epsilon 1
  • Vertebrate Orthologs
    20
  • Human Ortholog
    HBE1, hemoglobin subunit epsilon 1
    Orthology source: HomoloGene
  • Synonyms
    HBE
  • Links
    NCBI Gene ID: 3046
    neXtProt AC: NX_P02100

  • Chr Location
    11p15.5; chr11:5268345-5281945 (-)  GRCh38.p2

Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    12 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    27 phenotypes from multigenic genotypes
    68 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    3
  • Transgenic
    1
  • Genomic Mutations
    3 involving Hbb-bh1
  • Incidental Mutations
    APF
Mice with disruptions in this gene are grossly normal and viable through adulthood.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019079 VEGA Gene Model | MGI Sequence Detail 1528 C57BL/6J ±  kb
transcript OTTMUST00000045698 VEGA | MGI Sequence Detail 613 Not Applicable  
polypeptide OTTMUSP00000020569 VEGA | MGI Sequence Detail 147 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    109 from dbSNP Build 142
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 101
    Genomic 15
    cDNA 72
    Primer pair 13
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-10636
References
more
  • Summaries
    All 110
    Developmental Gene Expression 79
    Diseases 12
    Gene Ontology 5
    Phenotypes 68
  • Earliest
    J:6364 Jahn CL, et al., DNA sequence organization of the beta-globin complex in the BALB/c mouse. Cell. 1980 Aug;21(1):159-68
  • Latest
    J:224103 Papadopoulos P, et al., TAF10 Interacts with the GATA1 Transcription Factor and Controls Mouse Erythropoiesis. Mol Cell Biol. 2015 Jun;35(12):2103-18

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory