Hbb
Complex/Cluster/Region Detail

Symbol Name ID

Hbb hemoglobin beta chain complex MGI:96020

STS for

D7Nds7

Feature Type

complex/cluster/region

Genetic Map

Chromosome 7
Syntenic

Mapping data(172)

Alleles and phenotypes

All alleles(20) : Chemically induced (ENU)(5) Chemically induced (other)(1) Spontaneous(1) Targeted(9)
 

Mice homozygous or heterozygous for alleles of this gene exhibit varying degrees of hematopoietic defects.

 
Human Diseases Modeled Using Mouse Hbb (2)    Alleles Annotated to Human Diseases(6)    Phenotype Images(3)

Expression

Literature Summary: (15 records)

Data Summary: Results (9)    Tissues (7)   
Theiler Stages: 13, 15, 20, 22, 28

Assay Type	Results
Northern blot	7
RT-PCR	2

External Resources: Allen Institute  

Molecular reagents

All nucleic(17) Genomic(3) cDNA(7) Primer pair(5) Other(2)

Other database links

Entrez Gene

15127 (Evidence)

Sequences

Length

Strain/Species

All sequences(22) RefSeq(22)

Polymorphisms

All PCR and RFLP(13) : PCR(4) RFLP(9) SNPs within 2kb(0 from dbSNP Build 137)

References

(Earliest) J:110 Popp RA, et al., Studies on the mouse hemoglobin locus. I. Identification of hemoglobin types and linkage of hemoglobin with albinism. J Hered. 1960;51:141-144
(Latest) J:210302 Dussiot M, et al., An activin receptor IIA ligand trap corrects ineffective erythropoiesis in beta-thalassemia. Nat Med. 2014 Apr;20(4):398-407
All references(314)

Other accession IDs

MGD-MRK-10632