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Hbb Complex/Cluster/Region Detail
Summary
  • Symbol
    Hbb
  • Name
    hemoglobin beta chain complex
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:96020
    NCBI Gene: 15127
  • Cluster Members
    Hbb-bt, Hbb-bs, Hbb-bh3 ... (10 members)
Location & Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 7, Syntenic
  • Mapping Data
    173 experiments
  • Sequence Tag for
Human Diseases
more
  • Diseases
    1 with Hbb mouse models

Human Disease Mouse Models
      
IDs
View 6 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    13 with disease annotations
  • References
    11 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    48 phenotypes from 9 alleles in 8 genetic backgrounds
    111 phenotypes from multigenic genotypes
    3 images
    160 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous or heterozygous for alleles of this gene exhibit varying degrees of hematopoietic defects.
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Polymorphisms
    less
    • PCR
    • RFLP
    Molecular
    Reagents
    less
    • All nucleic 17
      Genomic 3
      cDNA 7
      Primer pair 5
      Other 2
    Other
    Accession IDs
    less
    MGD-MRK-10632
    References
    more
    • Summaries
      All 369
      Developmental Gene Expression 15
      Diseases 11
      Phenotypes 160
    • Earliest
      J:110 Popp RA, et al., Studies on the mouse hemoglobin locus. I. Identification of hemoglobin types and linkage of hemoglobin with albinism. J Hered. 1960;51:141-144
    • Latest
      J:247622 Pasricha SR, et al., Hepcidin is regulated by promoter-associated histone acetylation and HDAC3. Nat Commun. 2017 Sep 01;8(1):403

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    06/12/2018
    MGI 6.12
    The Jackson Laboratory