Hbb
Complex/Cluster/Region Detail

Symbol

Name
ID
Cluster members

Hbb
hemoglobin beta chain complex
MGI:96020
Hbb-bt, Hbb-bs, Hbb-bh3 ... (10 members)

STS for

D7Nds7

Feature Type

complex/cluster/region

Genetic Map

Chromosome 7
Syntenic

Mapping data(172)

Mutations,
alleles, and
phenotypes

All mutations/alleles(21) : Chemically induced (ENU)(5) Chemically induced (other)(1) Spontaneous(1) Targeted(9) Transgenic(5)
 

Mice homozygous or heterozygous for alleles of this gene exhibit varying degrees of hematopoietic defects.

 
Human Diseases Modeled in Mice Using Hbb (2)    Mutations Annotated to Human Diseases (11)    Phenotype Images(3)

Expression

Literature Summary: (15 records)

Data Summary: Results (9)    Tissues (7)    Tissue x Stage Matrix (view)

Assay Type	Results
Northern blot	7
RT-PCR	2

External Resources: Allen Institute  

Molecular
reagents

All nucleic(17) Genomic(3) cDNA(7) Primer pair(5) Other(2)

Other database
links

Entrez Gene

15127 (Evidence)

Sequences

Length

Strain/Species

All sequences(22) RefSeq(22)

Polymorphisms

All PCR and RFLP(13) : PCR(4) RFLP(9) SNPs within 2kb(0 from dbSNP Build 137)

References

(Earliest) J:110 Popp RA, et al., Studies on the mouse hemoglobin locus. I. Identification of hemoglobin types and linkage of hemoglobin with albinism. J Hered. 1960;51:141-144
(Latest) J:216540 Ning C, et al., Excess adenosine A2B receptor signaling contributes to priapism through HIF-1alpha mediated reduction of PDE5 gene expression. FASEB J. 2014 Jun;28(6):2725-35
All references(318)
Disease annotation references (12)

Other
accession IDs

MGD-MRK-10632

Hbb Cluster contains:

More Data for these features

Member	Feature Type	Location
Hbb-bt, hemoglobin, beta adult t chain	protein coding gene	Chr7:103812524-103813996 (-)
Hbb-bs, hemoglobin, beta adult s chain	protein coding gene	Chr7:103826534-103828096 (-)
Hbb-bh3, hemoglobin beta, pseudogene bh3	pseudogene	Chr7:103832631-103833723 (-)
Hbb-bh2, hemoglobin beta, bh2	protein coding gene	Chr7:103839145-103840427 (-)
Hbb-bh1, hemoglobin Z, beta-like embryonic chain	protein coding gene	Chr7:103841636-103843164 (-)
Hbb-bh0, hemoglobin, beta, pseudogene bh0	pseudogene	Chr7:103850020-103850148 (-)
Hbb-y, hemoglobin Y, beta-like embryonic chain	protein coding gene	Chr7:103851745-103853240 (-)
Hbb-ar, hemoglobin, activating region	unclassified other genome feature	Chr7, Syntenic
Hbb-b1, hemoglobin, beta adult major chain	protein coding gene	Chr7, Syntenic
Hbb-b2, hemoglobin, beta adult minor chain	protein coding gene	Chr7, Syntenic