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H2-T22 Gene Detail
Summary
  • Symbol
    H2-T22
  • Name
    histocompatibility 2, T region locus 22
  • Synonyms
    H-2T17, H2-T17, H-2T22
  • Feature Type
    protein coding gene
  • IDs
    MGI:95956
    NCBI Gene: 15039
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr17:36038407-36042743 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.87 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • Strain Annotations
    12
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95956
protein coding gene Chr17:36037128-36042747 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023668
protein coding gene Chr17:36259386-36360184 (-)
A/J MGP_AJ_G0023623
protein coding gene Chr17:35165759-35172843 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0023628
protein coding gene Chr17:35279371-35387947 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0024070
protein coding gene Chr17:37749698-37763279 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021430
protein coding gene Chr17:30253788-30258227 (-)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0023496
protein coding gene Chr17:34514517-34522413 (-)
FVB/NJ MGP_FVBNJ_G0023467
protein coding gene Chr17:34235848-34241491 (-)
LP/J MGP_LPJ_G0023576
protein coding gene Chr17:36627093-36731937 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023488
protein coding gene Chr17:38094178-38100891 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024112
protein coding gene Chr17:35871782-35982752 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0022951
protein coding gene Chr17:36021469-36027352 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 15039 NCBI Gene Model | MGI Sequence Detail 4337 C57BL/6J ±  kb
transcript NM_001347382 RefSeq | MGI Sequence Detail 2865 C57BL/6  
polypeptide NP_001346684 RefSeq | MGI Sequence Detail 379 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • PDB
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
    IPR011161 MHC class I-like antigen recognition-like
    IPR037055 MHC class I-like antigen recognition-like superfamily
Molecular
Reagents
less
  • All nucleic 25
    Genomic 8
    cDNA 14
    Primer pair 1
    Other 2

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-10432, MGD-MRK-10438, MGD-MRK-10545, MGD-MRK-10552, MGI:95949
References
more
  • Summaries
    All 27
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:20104 Steinmetz M, et al., Clusters of genes encoding mouse transplantation antigens. Cell. 1982 Mar;28(3):489-98
  • Latest
    J:261393 Fahl SP, et al., Role of a selecting ligand in shaping the murine gammadelta-TCR repertoire. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1889-1894

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory