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H2-DMb2 Gene Detail
Summary
  • Symbol
    H2-DMb2
  • Name
    histocompatibility 2, class II, locus Mb2
  • Synonyms
    H-2Mb2, H2-Mb2, H2-M beta2
  • Feature Type
    protein coding gene
  • IDs
    MGI:95923
    NCBI Gene: 15000
  • Gene Overview
    MyGene.info: HLA-DMB
Location & Maps
more
  • Sequence Map
    Chr17:34143307-34151553 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8247 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    HLA-DMB, major histocompatibility complex, class II, DM beta
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HLA-DMB, major histocompatibility complex, class II, DM beta
    Orthology source: HomoloGene, HGNC
  • Synonyms
    D6S221E, RING7
  • Links
    NCBI Gene ID: 3109
    neXtProt AC: NX_P28068

  • Chr Location
    6p21.32; chr6:32934629-32941070 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037091 VEGA Gene Model | MGI Sequence Detail 8247 C57BL/6J ±  kb
transcript OTTMUST00000095480 VEGA | MGI Sequence Detail 1347 Not Applicable  
polypeptide OTTMUSP00000053271 VEGA | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1 from dbSNP Build 142
Protein
Information
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  • UniProt
    18 Sequences
  • PDB
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR014745 MHC class II, alpha/beta chain, N-terminal
    IPR000353 MHC class II, beta chain, N-terminal
Molecular
Reagents
less
  • All nucleic 28
    Genomic 5
    cDNA 23

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-10407, MGD-MRK-10519
References
more
  • Summaries
    All 28
    Gene Ontology 7
  • Earliest
    J:10067 Strathmann M, et al., Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse. Proc Natl Acad Sci U S A. 1989 Oct;86(19):7407-9
  • Latest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory