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Slc39a7 Gene Detail
Summary
  • Symbol
    Slc39a7
  • Name
    solute carrier family 39 (zinc transporter), member 7
  • Synonyms
    H-2Ke4, H2-Ke4, Ke-4, KE4, Ring5, Zip7
  • Feature Type
    protein coding gene
  • IDs
    MGI:95909
    NCBI Gene: 14977
  • Gene Overview
    MyGene.info: SLC39A7
Location & Maps
more
  • Sequence Map
    Chr17:34028269-34031682 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      3414 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    SLC39A7, solute carrier family 39 member 7
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SLC39A7, solute carrier family 39 member 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    D6S115E, D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7
  • Links
    NCBI Gene ID: 7922
    neXtProt AC: NX_Q92504
    UniProt: Q92504

  • Chr Location
    6p21.32; chr6:33200826-33204437 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotypes from 1 allele in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a conditional allele activated in intestinal epithelial cells exhibit premature death, loss of epithelial integrity, reduced enterocyte proliferation and increased enterocyte apoptosis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    16
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    198
  • Tissues
    57
  • cDNA Data
    183
  • Literature Summary
    4
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035430 VEGA Gene Model | MGI Sequence Detail 3414 C57BL/6J ±  kb
transcript OTTMUST00000090595 VEGA | MGI Sequence Detail 2244 Not Applicable  
polypeptide OTTMUSP00000049736 VEGA | MGI Sequence Detail 476 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
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  • All nucleic 198
    Genomic 10
    cDNA 186
    Primer pair 2

    Microarray probesets 2
Other
Accession IDs
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MGD-MRK-10394, MGD-MRK-10505, MGI:2146748, MGI:2146797, MGI:2146956
References
more
  • Summaries
    All 50
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:9525 Abe K, et al., Searching for coding sequences in the mammalian genome: the H-2K region of the mouse MHC is replete with genes expressed in embryos. EMBO J. 1988 Nov;7(11):3441-9
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/12/2017
MGI 6.10 		The Jackson Laboratory