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H1f0 Gene Detail
Summary
  • Symbol
    H1f0
  • Name
    H1 histone family, member 0
  • Synonyms
    D130017D06Rik, H1fv
  • Feature Type
    protein coding gene
  • IDs
    MGI:95893
    NCBI Gene: 14958
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:79028450-79030504 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 37.70 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95893
protein coding gene Chr15:79028212-79030504 (.)
129S1/SvImJ MGP_129S1SvImJ_G0022060
protein coding gene Chr15:79283139-79285425 (+)
A/J MGP_AJ_G0022021
protein coding gene Chr15:76541572-76543858 (+)
AKR/J MGP_AKRJ_G0021996
protein coding gene Chr15:78660891-78663177 (+)
BALB/cJ MGP_BALBcJ_G0022027
protein coding gene Chr15:76515589-76517875 (+)
C3H/HeJ MGP_C3HHeJ_G0021798
protein coding gene Chr15:78665484-78667770 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022470
protein coding gene Chr15:82391700-82393986 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020000
protein coding gene Chr15:73025070-73027373 (+)
CAST/EiJ MGP_CASTEiJ_G0021319
protein coding gene Chr15:79357090-79359374 (+)
CBA/J MGP_CBAJ_G0021763
protein coding gene Chr15:84944846-84947132 (+)
DBA/2J MGP_DBA2J_G0021892
protein coding gene Chr15:76021786-76024072 (+)
FVB/NJ MGP_FVBNJ_G0021870
protein coding gene Chr15:75041318-75043604 (+)
LP/J MGP_LPJ_G0021960
protein coding gene Chr15:79467198-79469484 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021890
protein coding gene Chr15:90098580-90100866 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022484
protein coding gene Chr15:78686441-78688727 (+)
PWK/PhJ MGP_PWKPhJ_G0021061
protein coding gene Chr15:76026594-76028875 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020898
protein coding gene Chr15:78481436-78483721 (+)
WSB/EiJ MGP_WSBEiJ_G0021371
protein coding gene Chr15:79062177-79064463 (+)



Homology
more
  • Human Ortholog
    H1F0, H1 histone family member 0
  • Vertebrate Orthologs
    4
  • Human Ortholog
    H1F0, H1 histone family member 0
    Orthology source: HomoloGene, HGNC
  • Synonyms
    H10, H1FV
  • Links
    NCBI Gene ID: 3005
    neXtProt AC: NX_P07305
    UniProt: P07305

  • Chr Location
    22q13.1; chr22:37805107-37807436 (+)  GRCh38.p7

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotypes from multigenic genotypes
    25 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    2
  • Targeted
    1
  • Transgenic
    1
  • Genomic Mutations
    3 involving H1f0
  • Find Mice (IMSR)
Mice homozygous for a knock-out allele are viable, fertile and overtly normal with no apparent anatomic or histologic abnormalities or defects in cell division patterns.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000096210 Ensembl Gene Model | MGI Sequence Detail 2055 C57BL/6J ±  kb
transcript ENSMUST00000180086 Ensembl | MGI Sequence Detail 2055 Not Applicable  
polypeptide ENSMUSP00000137309 Ensembl | MGI Sequence Detail 194 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR005819 Histone H5
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013768 Intercellular adhesion molecule, N-terminal
    IPR005818 Linker histone H1/H5, domain H15
    IPR036390 Winged helix DNA-binding domain superfamily
    IPR036388 Winged helix-like DNA-binding domain superfamily
Molecular
Reagents
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  • All nucleic 24
    Genomic 3
    cDNA 19
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-10488, MGI:2444656
References
more
  • Summaries
    All 79
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 10
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:255180 Ichihara-Tanaka K, et al., Temporally and Spatially Regulated Expression of the Linker Histone H1fx During Mouse Development. J Histochem Cytochem. 2017 Sep;65(9):513-530

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory