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H13 Gene Detail
Summary
  • Symbol
    H13
  • Name
    histocompatibility 13
  • Synonyms
    1200006O09Rik, 4930443L17Rik, 5031424B04Rik, H-13, Spp
  • Feature Type
    protein coding gene
  • IDs
    MGI:95886
    NCBI Gene: 14950
  • Gene Overview
    MyGene.info: HM13
Location & Maps
more
  • Sequence Map
    Chr2:152669461-152708670 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      39210 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 75.41 cM
  • Mapping Data
    10 experiments
Homology
more
  • Human Ortholog
    HM13, histocompatibility minor 13
  • Vertebrate Orthologs
    8
  • Human Ortholog
    HM13, histocompatibility minor 13
    Orthology source: HGNC, HomoloGene
  • Synonyms
    H13, IMP1, IMPAS, IMPAS-1, MSTP086, PSENL3, PSL3, SPP, SPPL1
  • Links
    NCBI Gene ID: 81502
    neXtProt AC: NX_Q8TCT9

  • Chr Location
    20q11.21; chr20:31514410-31569567 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    31
  • Chemically induced (other)
    1
  • Gene trapped
    27
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving H13
  • Incidental Mutations
This is one of several loci identified by development of congenic strains differing in resistance to transplantable tumors. C57BL/10 carries the a allele and B10.129(14M) carries the b allele.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015824 VEGA Gene Model | MGI Sequence Detail 39210 C57BL/6J ±  kb
transcript OTTMUST00000037623 VEGA | MGI Sequence Detail 1743 Not Applicable  
polypeptide OTTMUSP00000016863 VEGA | MGI Sequence Detail 394 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    335 from dbSNP Build 142
  • RFLP
Protein
Information
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Molecular
Reagents
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  • All nucleic 184
    cDNA 180
    Primer pair 4

    Microarray probesets 10
Other
Accession IDs
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MGD-MRK-10359, MGD-MRK-10481, MGI:1914866, MGI:1915400, MGI:2139237, MGI:2447815
References
more
  • Summaries
    All 53
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:5026 Graff RJ, et al., Histocompatibility genes of mice. VI. Allografts in mice congenic at various non-H-2 histocompatibility loci. Transplantation. 1966 Jul;4(4):425-37
  • Latest
    J:206256 Oliveira CC, et al., New role of signal peptide peptidase to liberate C-terminal peptides for MHC class I presentation. J Immunol. 2013 Oct 15;191(8):4020-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory