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Gypa
Gene Detail
Symbol

Name
ID
Gypa
glycophorin A
MGI:95880
Synonyms
CD235a, GPA
Feature Type
protein coding gene
Genetic Map
Chromosome 8
38.27 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr8:80494045-80510785 bp, + strand
From Ensembl annotation of GRCm38

  16741 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: glycophorin
Gene Tree: Gypa
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted null mutation are viable and fertile; however, mutant erythrocytes had a reduced percentage of O-linked glycoproteins in the membranes, and were sensitive to hypoosmotic stress.
 
Interactions
Gypa interacts with 182 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (4)    Tissues (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 4
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(20) Genomic(4) cDNA(14) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000051839 (Evidence)
Entrez Gene14934 (Evidence)
UniGene13123
DFCITC1588850, TC1720716
DoTSDT.529576, DT.94399413
NIA Mouse Gene IndexU075445
Consensus CDS ProjectCCDS40399.1
International Mouse Knockout Project StatusGypa
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051839 Ensembl Gene Model | MGI Sequence Detail 16741 C57BL/6J ±  kb
transcript ENSMUST00000063359 Ensembl | MGI Sequence Detail 1827 Not Applicable 
polypeptide ENSMUSP00000070836 Ensembl | MGI Sequence Detail 168 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(4) UniProt(7)
Polymorphisms
RFLP(2) : SNPs within 2kb(119 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001195 Glycophorin
InterPro IPR018938 Glycophorin, conserved site
Protein Ontology PR:000001460 glycophorin-A
References
(Earliest) J:9899 Matsui Y, et al., Isolation of the cDNA clone for mouse glycophorin, erythroid-specific membrane protein. Gene. 1989 Apr 30;77(2):325-32
(Latest) J:186666 Pang CJ, et al., Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis. Mol Cell Biol. 2012 Jul;32(13):2628-44
All references(40)
Other
accession IDs
MGD-MRK-10344, MGI:2142640

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory