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Gsta2 Gene Detail
Summary
  • Symbol
    Gsta2
  • Name
    glutathione S-transferase, alpha 2 (Yc2)
  • Synonyms
    Gst2-2, Gstc2, Gstc-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:95863
    NCBI Gene: 14858
  • Member of
    Gsta cluster
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:78331018-78347192 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 43.65 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    248 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95863
protein coding gene Chr9:78331018-78355788 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0035041
protein coding gene Chr9:76009953-76020825 (+)
AKR/J MGP_AKRJ_G0034970
protein coding gene Chr9:77773553-77866523 (+)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0034715
protein coding gene Chr9:83619264-83643364 (+)
DBA/2J MGP_DBA2J_G0034877
protein coding gene Chr9:75732798-75761272 (-)
FVB/NJ MGP_FVBNJ_G0034816
protein coding gene Chr9:74864900-74935057 (+)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0034858
protein coding gene Chr9:84813821-84837361 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035578
protein coding gene Chr9:78061367-78088579 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0033604
protein coding gene Chr9:78260090-78293971 (-)
WSB/EiJ MGP_WSBEiJ_G0034177
protein coding gene Chr9:77888578-77908030 (+)



Homology
more
  • Human Ortholog
    GSTA5, glutathione S-transferase alpha 5
  • Vertebrate Orthologs
    8
  • Human Ortholog
    GSTA5, glutathione S-transferase alpha 5
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 221357
    neXtProt AC: NX_Q7RTV2
    UniProt: Q7RTV2

  • Chr Location
    6p12.2; chr6:52831742-52846095 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14858 NCBI Gene Model | MGI Sequence Detail 16175 C57BL/6J ±  kb
transcript NM_008182 RefSeq | MGI Sequence Detail 855 C57BL/6  
polypeptide P10648 UniProt | EBI | MGI Sequence Detail 222 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • PDB
  • EC
  • InterPro Domains
    IPR003080 Glutathione S-transferase, alpha class
    IPR004046 Glutathione S-transferase, C-terminal
    IPR036282 Glutathione S-transferase, C-terminal domain superfamily
    IPR010987 Glutathione S-transferase, C-terminal-like
    IPR004045 Glutathione S-transferase, N-terminal
    IPR040079 Glutathione Transferase family
    IPR036249 Thioredoxin-like superfamily
Molecular
Reagents
less
  • All nucleic 31
    cDNA 31

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-10309, MGD-MRK-10321, MGD-MRK-10322, MGI:95855
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:12013 Russell LB, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971 Jan;11(1):107-23
  • Latest
    J:190322 Archambaud C, et al., Impact of lactobacilli on orally acquired listeriosis. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16684-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory