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Gstm4 Gene Detail
Summary
  • Symbol
    Gstm4
  • Name
    glutathione S-transferase, mu 4
  • Synonyms
    1110004G14Rik, Gstb4, Gstb-4
  • Feature Type
    protein coding gene
  • IDs
    MGI:95862
    NCBI Gene: 14865
  • Gene Overview
    MyGene.info: GSTM4
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:108040408-108044894 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 46.83 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    89 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95862
protein coding gene Chr3:108030570-108045082 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027763
protein coding gene Chr3:109567102-109571369 (-)
A/J MGP_AJ_G0027723
protein coding gene Chr3:106097667-106101934 (-)
AKR/J MGP_AKRJ_G0027688
protein coding gene Chr3:108684791-108688227 (-)
BALB/cJ MGP_BALBcJ_G0027735
protein coding gene Chr3:105800577-105804844 (-)
C3H/HeJ MGP_C3HHeJ_G0027465
protein coding gene Chr3:109024773-109029040 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028179
protein coding gene Chr3:113663574-113667841 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025517
protein coding gene Chr3:102252409-102256996 (-)
CAST/EiJ MGP_CASTEiJ_G0026921
protein coding gene Chr3:108405405-108409894 (-)
CBA/J MGP_CBAJ_G0027440
protein coding gene Chr3:117526286-117530553 (-)
DBA/2J MGP_DBA2J_G0027582
protein coding gene Chr3:105281546-105285813 (-)
FVB/NJ MGP_FVBNJ_G0027550
protein coding gene Chr3:103168595-103172862 (-)
LP/J MGP_LPJ_G0027689
protein coding gene Chr3:110990853-110995120 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027580
protein coding gene Chr3:123601328-123605595 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028234
protein coding gene Chr3:108276404-108279841 (-)
PWK/PhJ MGP_PWKPhJ_G0026647
protein coding gene Chr3:105029787-105033219 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026467
protein coding gene Chr3:106411168-106414605 (-)
WSB/EiJ MGP_WSBEiJ_G0027001
protein coding gene Chr3:108804434-108808701 (-)



Homology
more
  • Human Ortholog
    GSTM4, glutathione S-transferase mu 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GSTM4, glutathione S-transferase mu 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GSTM4-4, GTM4
  • Links
    NCBI Gene ID: 2948
    neXtProt AC: NX_Q03013
    UniProt: Q03013

  • Chr Location
    1p13.3; chr1:109656076-109665501 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027890 Ensembl Gene Model | MGI Sequence Detail 4487 C57BL/6J ±  kb
    transcript ENSMUST00000029489 Ensembl | MGI Sequence Detail 1707 Not Applicable  
    polypeptide ENSMUSP00000029489 Ensembl | MGI Sequence Detail 218 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • EC
    • InterPro Domains
      IPR004046 Glutathione S-transferase, C-terminal
      IPR036282 Glutathione S-transferase, C-terminal domain superfamily
      IPR010987 Glutathione S-transferase, C-terminal-like
      IPR003081 Glutathione S-transferase, Mu class
      IPR004045 Glutathione S-transferase, N-terminal
      IPR040079 Glutathione Transferase family
      IPR036249 Thioredoxin-like superfamily
    Molecular
    Reagents
    less
    • All nucleic 29
      cDNA 28
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-10316, MGD-MRK-10320, MGI:1915805
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 3
      Phenotypes 8
    • Earliest
      J:4644 Reinhart J, et al., The structure of two murine class-mu glutathione transferase genes coordinately induced by butylated hydroxyanisole. Arch Biochem Biophys. 1993 Jun;303(2):383-93
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    06/11/2019
    MGI 6.14
    The Jackson Laboratory