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Grp
Gene Detail
Symbol

Name
ID
Grp
gastrin releasing peptide
MGI:95833
Synonyms
BLP, MGC:37475
Feature Type
protein coding gene
Genetic Map
Chromosome 18
38.98 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:65872820-65886579 bp, + strand
From VEGA annotation of GRCm38

  13760 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1580  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 chicken

Protein SuperFamily: gastrin-releasing peptide
Gene Tree: Grp

Human
homologs
Human Homolog GRP, gastrin-releasing peptide
NCBI Gene ID 2922
neXtProt AC  NX_P07492
Human Synonyms  BN, GRP-10, preproGRP, proGRP
Human Chr (Location)  18q21.1-q21.32; chr18:59220168-59230771 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(6) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Grp interacts with 78 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process neuropeptide signaling pathway
Component extracellular region, extracellular space
Function neuropeptide hormone activity
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (153)    Tissues (119)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 131
RT-PCR 22
cDNA source data(7)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(8) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000037740 (Evidence)
Ensembl Gene ModelENSMUSG00000024517 (Evidence)
Entrez Gene225642 (Evidence)
DFCITC1583810, TC1716511
DoTSDT.523098, DT.91562417
NIA Mouse Gene IndexU166423
Consensus CDS ProjectCCDS29310.1
International Mouse Knockout Project StatusGrp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037740 VEGA Gene Model | MGI Sequence Detail 13760 C57BL/6J ±  kb
transcript OTTMUST00000097465 VEGA | MGI Sequence Detail 952 Not Applicable 
polypeptide OTTMUSP00000054666 VEGA | MGI Sequence Detail 146 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(6) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(158 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000874 Bombesin/neuromedin-B/ranatensin peptide family
InterPro IPR015674 Gastrin releasing peptide
Protein Ontology PR:000031729 gastrin-releasing peptide
References
(Earliest) J:15302 Spindel ER, et al., Cloning and characterization of cDNAs encoding human gastrin-releasing peptide. Proc Natl Acad Sci U S A. 1984 Sep;81(18):5699-703
(Latest) J:205122 Zhao ZQ, et al., Chronic itch development in sensory neurons requires BRAF signaling pathways. J Clin Invest. 2013 Nov 1;123(11):4769-80
All references(44)
Other
accession IDs
MGD-MRK-10273

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory