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Grid1
Gene Detail
 Symbol
Name
ID
Grid1
glutamate receptor, ionotropic, delta 1
MGI:95812
Synonyms GluRdelta1
Feature Type protein coding gene
Genetic Map
Chromosome 14
20.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:34819825-35583379 bp, + strand
From VEGA annotation of GRCm38

  763555 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69017  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: ionotropic glutamate receptor delta
Gene Tree: Grid1

Human
homologs
Human Homolog GRID1, glutamate receptor, ionotropic, delta 1
NCBI Gene ID 2894
neXtProt AC  NX_Q9ULK0
Human Synonyms  GluD1
Human Chr (Location)  10q22; chr10:85599555-86366493 (-)  GRCh38
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for a targeted null mutation display a significant high-frequency hearing loss, associated with reductions of both cochlear outer hair cell function and endolymphatic potential, as well as increased vulnerability to acoustic injury.
 
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process ionotropic glutamate receptor signaling pathway, ion transmembrane transport, ...
Component cell junction, dendrite, ...
Function extracellular-glutamate-gated ion channel activity, ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (227)    Tissues (77)    Images (33)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 135
RT-PCR 92
cDNA source data(8)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(10) cDNA(8) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000033220 (Evidence)
Ensembl Gene ModelENSMUSG00000041078 (Evidence)
Entrez Gene14803 (Evidence)
DFCITC1589369, TC1700837
DoTSDT.40139882
NIA Mouse Gene IndexU015503, U202312
Consensus CDS ProjectCCDS26944.1
International Mouse Knockout Project StatusGrid1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033220 VEGA Gene Model | MGI Sequence Detail 763555 C57BL/6J ±  kb
transcript OTTMUST00000083227 VEGA | MGI Sequence Detail 6003 Not Applicable 
polypeptide OTTMUSP00000044686 VEGA | MGI Sequence Detail 1009 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(8) UniProt(1)
Polymorphisms PCR(1) : SNPs within 2kb(6979 from dbSNP Build 137)    SNPs within 2kb including multiple locations(6995)
Protein-related
information
ResourceIDDescription
InterPro IPR001828 Extracellular ligand-binding receptor
InterPro IPR001638 Extracellular solute-binding protein, family 3
InterPro IPR019594 Glutamate receptor, L-glutamate/glycine-binding
InterPro IPR001320 Ionotropic glutamate receptor
InterPro IPR001508 NMDA receptor
Protein Ontology PR:000008237 glutamate receptor ionotropic, delta-1
References (Earliest) J:320 Yamazaki M, et al., Molecular cloning of a cDNA encoding a novel member of the mouse glutamate receptor channel family. Biochem Biophys Res Commun. 1992 Mar 16;183(2):886-92
(Latest) J:205639 Yadav R, et al., Deletion of glutamate delta-1 receptor in mouse leads to aberrant emotional and social behaviors. PLoS One. 2012;7(3):e32969
All references(37)
Other
accession IDs
MGD-MRK-10250

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory