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Gng7
Gene Detail
Symbol

Name
ID
Gng7
guanine nucleotide binding protein (G protein), gamma 7
MGI:95787
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr10:80948624-81014945 bp, - strand
From VEGA annotation of GRCm38

  66322 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31293  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GNG7
Protein SuperFamily: GTP-binding regulatory protein gamma chain
Gene Tree: Gng7

Human
homologs
GNG7, guanine nucleotide binding protein (G protein), gamma 7
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 2788
neXtProt AC: NX_O60262

Human Chr (Location): 19p13.3; chr19:2511220-2702748 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(117) : Gene trapped(108) Targeted(9)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit an enhanced startle response, loss of dopamine- and forskolin-stimulated adenylyl cyclase activity in the striatum, and increased mean insulin levels in males.
 
Phenotype Images(1)
Interactions
Gng7 interacts with 283 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process behavioral fear response, G-protein coupled receptor signaling pathway, ...
Component extracellular exosome, heterotrimeric G-protein complex, ...
Function signal transducer activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (110)    Tissues (38)    Images (52)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 103
RT-PCR 7
cDNA source data(21)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase gng7 ; ZFIN gng7    NEW 
Molecular
reagents
All nucleic(22) cDNA(21) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000030294 (Evidence)
Ensembl Gene Model ENSMUSG00000048240 (Evidence)
Entrez Gene 14708 (Evidence)
UniGene 222496
DFCI TC1585194, TC1604854, TC1626539
DoTS DT.101377940, DT.110603524, DT.40182368
NIA Mouse Gene Index U032029
Consensus CDS Project CCDS24039.1
International Mouse Phenotyping Consortium Status Gng7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030294 VEGA Gene Model | MGI Sequence Detail 66322 C57BL/6J ±  kb
transcript OTTMUST00000075007 VEGA | MGI Sequence Detail 875 Not Applicable 
polypeptide OTTMUSP00000039249 VEGA | MGI Sequence Detail 68 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(6) UniProt(5)
Polymorphisms
RFLP(1) : SNPs within 2kb(125 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015898 G-protein gamma-like domain
InterPro IPR001770 G-protein, gamma subunit
Protein Ontology PR:000008111 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
References
(Earliest) J:22157 Cali JJ, et al., Selective tissue distribution of G protein gamma subunits, including a new form of the gamma subunits identified by cDNA cloning. J Biol Chem. 1992 Nov 25;267(33):24023-7
(Latest) J:210178 Ikegami M, et al., Striatal dopamine D1 receptor is essential for contextual fear conditioning. Sci Rep. 2014;4:3976
All references(45)
Other
accession IDs
MGD-MRK-10206, MGI:2143677

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory