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Gnb2 Gene Detail
Summary
  • Symbol
    Gnb2
  • Name
    guanine nucleotide binding protein (G protein), beta 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:95784
    NCBI Gene: 14693
  • Gene Overview
    MyGene.info: GNB2
Location & Maps
more
  • Sequence Map
    Chr5:137528127-137533510 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5384 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 76.54 cM
  • Mapping Data
    9 experiments
Homology
more
  • Human Ortholog
    GNB2, G protein subunit beta 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    GNB2, G protein subunit beta 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 2783
    neXtProt AC: NX_P62879

  • Chr Location
    7q22; chr7:100673740-100679169 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Targeted
    2
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016277 VEGA Gene Model | MGI Sequence Detail 5384 C57BL/6J ±  kb
transcript OTTMUST00000042585 VEGA | MGI Sequence Detail 1610 Not Applicable  
polypeptide OTTMUSP00000019137 VEGA | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    12 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000008097 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
  • InterPro Domains
    IPR001632 G-protein, beta subunit
    IPR020472 G-protein beta WD-40 repeat
    IPR016346 Guanine nucleotide-binding protein, beta subunit
    IPR001680 WD40 repeat
    IPR019775 WD40 repeat, conserved site
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
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  • All nucleic 375
    Genomic 1
    cDNA 371
    Primer pair 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-10197, MGD-MRK-10203
References
more
  • Summaries
    All 50
    Developmental Gene Expression 7
    Gene Ontology 8
    Phenotypes 3
  • Earliest
    J:31005 Fong HK, et al., Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning. Proc Natl Acad Sci U S A. 1987 Jun;84(11):3792-6
  • Latest
    J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory