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Gnb2
Gene Detail
 Symbol
Name
ID
Gnb2
guanine nucleotide binding protein (G protein), beta 2
MGI:95784
Feature Type protein coding gene
Genetic Map
Chromosome 5
76.54 cM
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr5:137528127-137533510 bp, - strand
From VEGA annotation of GRCm38

  5384 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68451  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 zebrafish

Protein SuperFamily: guanine nucleotide-binding protein, beta subunit
Gene Tree: Gnb2

Human
homologs
Human Homolog GNB2, guanine nucleotide binding protein (G protein), beta polypeptide 2
NCBI Gene ID 2783
neXtProt AC  NX_P62879
Human Chr (Location)  7q22; chr7:100673740-100679169 (+)  GRCh38
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
Incidental mutations (data from APF )
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process G-protein coupled receptor signaling pathway, GTP catabolic process, ...
Component cell body, cytoplasm, ...
Function calcium channel regulator activity, GTPase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (18)    Tissues (17)    Images (3)
Theiler Stages: 1, 2, 3, 4, 22, 28
Assay TypeResults
RNA in situ 1
RT-PCR 17
cDNA source data(370)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(375) Genomic(1) cDNA(371) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000016277 (Evidence)
Ensembl Gene ModelENSMUSG00000029713 (Evidence)
Entrez Gene14693 (Evidence)
UniGene30141
DFCITC1573269
DoTSDT.110671893, DT.496274
NIA Mouse Gene IndexU026848
Consensus CDS ProjectCCDS19769.1
International Mouse Knockout Project StatusGnb2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016277 VEGA Gene Model | MGI Sequence Detail 5384 C57BL/6J ±  kb
transcript OTTMUST00000042585 VEGA | MGI Sequence Detail 1610 Not Applicable 
polypeptide OTTMUSP00000019137 VEGA | MGI Sequence Detail 382 Not Applicable 

For the selected sequences
All sequences(83) RefSeq(4) UniProt(8)
Polymorphisms RFLP(1) : SNPs within 2kb(13 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001632 G-protein, beta subunit
InterPro IPR020472 G-protein beta WD-40 repeat
InterPro IPR016346 Guanine nucleotide-binding protein, beta subunit
InterPro IPR001680 WD40 repeat
InterPro IPR019775 WD40 repeat, conserved site
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000008097 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
References (Earliest) J:31005 Fong HK, et al., Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning. Proc Natl Acad Sci U S A. 1987 Jun;84(11):3792-6
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(55)
Other
accession IDs
MGD-MRK-10197, MGD-MRK-10203

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory