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Gna15 Gene Detail
Summary
  • Symbol
    Gna15
  • Name
    guanine nucleotide binding protein, alpha 15
  • Synonyms
    G[a]15, Galpha15
  • Feature Type
    protein coding gene
  • IDs
    MGI:95770
    NCBI Gene: 14676
  • Alliance
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:81502306-81524225 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    14 experiments
Strain
Comparison
more
  • SNPs within 2kb
    108 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95770
protein coding gene Chr10:81502306-81524483 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017563
protein coding gene Chr10:82228130-82250600 (-)
A/J MGP_AJ_G0017541
protein coding gene Chr10:79307773-79330055 (-)
AKR/J MGP_AKRJ_G0017502
protein coding gene Chr10:81483382-81506922 (-)
BALB/cJ MGP_BALBcJ_G0017503
protein coding gene Chr10:79530763-79552629 (-)
C3H/HeJ MGP_C3HHeJ_G0017326
protein coding gene Chr10:81588746-81611617 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017957
protein coding gene Chr10:85047042-85069716 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015646
protein coding gene Chr10:75506215-75527372 (-)
CAST/EiJ MGP_CASTEiJ_G0016893
protein coding gene Chr10:81827214-81852848 (-)
CBA/J MGP_CBAJ_G0017298
protein coding gene Chr10:88381277-88407296 (-)
DBA/2J MGP_DBA2J_G0017404
protein coding gene Chr10:78513502-78534868 (-)
FVB/NJ MGP_FVBNJ_G0017398
protein coding gene Chr10:77774290-77798185 (-)
LP/J MGP_LPJ_G0017475
protein coding gene Chr10:82675535-82701776 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017424
protein coding gene Chr10:90208793-90236573 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017998
protein coding gene Chr10:81496156-81523435 (-)
PWK/PhJ MGP_PWKPhJ_G0016674
protein coding gene Chr10:78418220-78440007 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016464
protein coding gene Chr10:80449894-80472505 (-)
WSB/EiJ MGP_WSBEiJ_G0016953
protein coding gene Chr10:81542475-81566889 (-)



Homology
more
  • Human Ortholog
    GNA15, G protein subunit alpha 15
  • Vertebrate Orthologs
    8
  • Human Ortholog
    GNA15, G protein subunit alpha 15
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GNA16
  • Links
    NCBI Gene ID: 2769
    neXtProt AC: NX_P30679
    UniProt: P30679

  • Chr Location
    19p13.3; chr19:3136032-3163769 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    15 phenotype references
Mice homozygous for a targeted null mutation exhibit normal hematopoiesis and normal response to inflammatory challenges.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034792 Ensembl Gene Model | MGI Sequence Detail 21920 C57BL/6J ±  kb
transcript ENSMUST00000043709 Ensembl | MGI Sequence Detail 1962 Not Applicable  
polypeptide ENSMUSP00000049175 Ensembl | MGI Sequence Detail 374 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000008084 guanine nucleotide-binding protein subunit alpha-15
  • InterPro Domains
    IPR000654 G-protein alpha subunit, group Q
    IPR011025 G protein alpha subunit, helical insertion
    IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 35
    Genomic 17
    cDNA 17
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-10179
References
more
  • Summaries
    All 55
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 15
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:272723 Wang Q, et al., Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle. Curr Biol. 2017 Jun 19;27(12):1791-1800.e5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory