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Gna14 Gene Detail
Summary
  • Symbol
    Gna14
  • Name
    guanine nucleotide binding protein, alpha 14
  • Synonyms
    G alpha 14
  • Feature Type
    protein coding gene
  • IDs
    MGI:95769
    NCBI Gene: 14675
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:16435667-16610818 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 11.29 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1381 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95769
protein coding gene Chr19:16435667-16610818 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024959
protein coding gene Chr19:14165166-14367970 (+)
A/J MGP_AJ_G0024936
protein coding gene Chr19:13358667-13542348 (+)
AKR/J MGP_AKRJ_G0024906
protein coding gene Chr19:13904496-14085430 (+)
BALB/cJ MGP_BALBcJ_G0024935
protein coding gene Chr19:13398249-13576591 (+)
C3H/HeJ MGP_C3HHeJ_G0024693
protein coding gene Chr19:13845662-14032313 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025377
protein coding gene Chr19:14736510-14926736 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022796
protein coding gene Chr19:13801597-13965546 (+)
CAST/EiJ MGP_CASTEiJ_G0024161
protein coding gene Chr19:13424691-13609885 (+)
CBA/J MGP_CBAJ_G0024671
protein coding gene Chr19:15184312-15394508 (+)
DBA/2J MGP_DBA2J_G0024803
protein coding gene Chr19:13399012-13575428 (+)
FVB/NJ MGP_FVBNJ_G0024764
protein coding gene Chr19:13318784-13493777 (+)
LP/J MGP_LPJ_G0024887
protein coding gene Chr19:14171083-14358226 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024791
protein coding gene Chr19:15112539-15308077 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025432
protein coding gene Chr19:13821862-14010898 (+)
PWK/PhJ MGP_PWKPhJ_G0023910
protein coding gene Chr19:12928942-13096987 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023715
protein coding gene Chr19:13123657-13298974 (+)
WSB/EiJ MGP_WSBEiJ_G0024229
protein coding gene Chr19:13849944-14040394 (+)



Homology
more
  • Human Ortholog
    GNA14, G protein subunit alpha 14
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GNA14, G protein subunit alpha 14
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 9630
    neXtProt AC: NX_O95837
    UniProt: O95837

  • Chr Location
    9q21.2; chr9:77423079-77648316 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 68386
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GNA14
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14675 NCBI Gene Model | MGI Sequence Detail 175152 C57BL/6J ±  kb
transcript NM_008137 RefSeq | MGI Sequence Detail 3383 C57BL/6  
polypeptide P30677 UniProt | EBI | MGI Sequence Detail 355 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000008083 guanine nucleotide-binding protein subunit alpha-14
  • InterPro Domains
    IPR000654 G-protein alpha subunit, group Q
    IPR011025 G protein alpha subunit, helical insertion
    IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 36
    cDNA 34
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-10178, MGI:2147654
References
more
  • Summaries
    All 40
    Developmental Gene Expression 8
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:10067 Strathmann M, et al., Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse. Proc Natl Acad Sci U S A. 1989 Oct;86(19):7407-9
  • Latest
    J:232057 Hughes S, et al., Using siRNA to define functional interactions between melanopsin and multiple G Protein partners. Cell Mol Life Sci. 2015 Jan;72(1):165-79

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
01/08/2019
MGI 6.13
The Jackson Laboratory