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Slc6a9
Gene Detail
Symbol

Name
ID
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
MGI:95760
Synonyms
Glyt1, Glyt-1
Feature Type
protein coding gene
Genetic Map
Chromosome 4
53.62 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:117834506-117875198 bp, + strand
From VEGA annotation of GRCm38

  40693 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5050  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SLC6A9
Gene Tree: Slc6a9

Human
homologs
SLC6A9, solute carrier family 6 (neurotransmitter transporter, glycine), member 9
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6536
neXtProt AC: NX_P48067

Human Synonyms: GLYT1

Human Chr (Location): 1p33; chr1:43996483-44031492 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Targeted(10)
Genomic Mutations involving Slc6a9 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygous null mice die shortly after birth exhibiting breathing and movement deficiencies.
 
Human Diseases Modeled in Mice Using Slc6a9 (1)    Mutations Annotated to Human Diseases (1)   
Interactions
Slc6a9 interacts with 218 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (27 records)
Data Summary: Results (321)    Tissues (153)    Images (82)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 145
In situ reporter (knock in) 72
RT-PCR 91
RNase protection 13
cDNA source data(11)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase slc6a9 ; ZFIN slc6a9    NEW 
Molecular
reagents
All nucleic(23) Genomic(5) cDNA(15) Primer pair(3)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000008656 (Evidence)
Ensembl Gene Model ENSMUSG00000028542 (Evidence)
Entrez Gene 14664 (Evidence)
DFCI TC1576555, TC1625558, TC1777042
Consensus CDS Project CCDS18538.1
International Mouse Phenotyping Consortium Status Slc6a9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008656 VEGA Gene Model | MGI Sequence Detail 40693 C57BL/6J ±  kb
transcript OTTMUST00000090034 VEGA | MGI Sequence Detail 2107 Not Applicable 
polypeptide OTTMUSP00000049290 VEGA | MGI Sequence Detail 637 Not Applicable 

For the selected sequences
All sequences(76) RefSeq(7) UniProt(7)
Polymorphisms
RFLP(1) : SNPs within 2kb(223 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000175 Sodium:neurotransmitter symporter
InterPro IPR003028 Sodium:neurotransmitter symporter, glycine, type 1
Protein Ontology PR:000015193 sodium- and chloride-dependent glycine transporter 1
References
(Earliest) J:1378 Liu QR, et al., Cloning and expression of a glycine transporter from mouse brain. FEBS Lett. 1992 Jun 29;305(2):110-4
(Latest) J:217063 Zou M, et al., Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Dev Dyn. 2015 Jan;244(1):86-97
All references(73)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-10166, MGD-MRK-10167

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory