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Slc6a9
Gene Detail
 Symbol
Name
ID
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
MGI:95760
Synonyms Glyt1, Glyt-1
Feature Type protein coding gene
Genetic Map
Chromosome 4
53.62 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:117834506-117875198 bp, + strand
From VEGA annotation of GRCm38

  40693 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5050  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Slc6a9

Human
homologs
Human Homolog SLC6A9, solute carrier family 6 (neurotransmitter transporter, glycine), member 9
NCBI Gene ID 6536
neXtProt AC  NX_P48067
Human Synonyms  GLYT1
Human Chr (Location)  1p33; chr1:43996483-44031492 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Targeted(9)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice die shortly after birth exhibiting breathing and movement deficiencies.
 
Human Diseases Modeled Using Mouse Slc6a9 (1)    Alleles Annotated to Human Diseases(1)   
Interactions
Slc6a9 interacts with 218 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process amino acid transport, cation transmembrane transport, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function glycine transmembrane transporter activity, neurotransmitter:sodium symporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (25 records)
Data Summary: Results (321)    Tissues (153)    Images (82)
Theiler Stages: 1, 2, 3, 4, 15, 17, 19, 20, 21, 22, 23, 24, 25, 27, 28
Assay TypeResults
RNA in situ 145
In situ reporter (knock in) 72
RT-PCR 91
RNase protection 13
cDNA source data(11)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) Genomic(5) cDNA(15) Primer pair(3)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000008656 (Evidence)
Ensembl Gene ModelENSMUSG00000028542 (Evidence)
Entrez Gene14664 (Evidence)
DFCITC1576555, TC1625558, TC1777042
Consensus CDS ProjectCCDS18538.1
International Mouse Knockout Project StatusSlc6a9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008656 VEGA Gene Model | MGI Sequence Detail 40693 C57BL/6J ±  kb
transcript OTTMUST00000090034 VEGA | MGI Sequence Detail 2107 Not Applicable 
polypeptide OTTMUSP00000049290 VEGA | MGI Sequence Detail 637 Not Applicable 

For the selected sequences
All sequences(74) RefSeq(5) UniProt(7)
Polymorphisms RFLP(1) : SNPs within 2kb(223 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000175 Sodium:neurotransmitter symporter
InterPro IPR003028 Sodium:neurotransmitter symporter, glycine, type 1
Protein Ontology PR:000015193 sodium- and chloride-dependent glycine transporter 1
References (Earliest) J:1378 Liu QR, et al., Cloning and expression of a glycine transporter from mouse brain. FEBS Lett. 1992 Jun 29;305(2):110-4
(Latest) J:203021 Kunz PA, et al., Glycine receptors support excitatory neurotransmitter release in developing mouse visual cortex. J Physiol. 2012 Nov 15;590(Pt 22):5749-64
All references(71)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-10166, MGD-MRK-10167

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory