About   Help   FAQ
Glra3
Gene Detail
 Symbol
Name
ID
Glra3
glycine receptor, alpha 3 subunit
MGI:95749
Feature Type protein coding gene
Genetic Map
Chromosome 8
29.69 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:55940460-56125429 bp, + strand
From VEGA annotation of GRCm38

  184970 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:142  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Glra3

Human
homologs
Human Homolog GLRA3, glycine receptor, alpha 3
NCBI Gene ID 8001
neXtProt AC  NX_O75311
Human Chr (Location)  4q34.1; chr4:174642011-174829315 (-)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
 
Homozygous null mice are fertile and display decreased inflammatory pain sensitization without any gross abnormalities in the brain or spinal cord.
 
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process chloride transmembrane transport, chloride transport, ...
Component cell junction, chloride channel complex, ...
Function chloride channel activity, extracellular-glycine-gated chloride channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (85)    Tissues (48)    Images (15)
Theiler Stages: 23, 28
Assay TypeResults
RNA in situ 7
In situ reporter (knock in) 40
RT-PCR 38
cDNA source data(2)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(6) cDNA(3) Primer pair(1) Other(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000036483 (Evidence)
Ensembl Gene ModelENSMUSG00000038257 (Evidence)
Entrez Gene110304 (Evidence)
UniGene307061
DFCITC1590941, TC1655152
DoTSDT.101708472, DT.91446554
NIA Mouse Gene IndexU009347
Consensus CDS ProjectCCDS40340.1
International Mouse Knockout Project StatusGlra3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036483 VEGA Gene Model | MGI Sequence Detail 184970 C57BL/6J ±  kb
transcript OTTMUST00000093512 VEGA | MGI Sequence Detail 1867 Not Applicable 
polypeptide OTTMUSP00000051884 VEGA | MGI Sequence Detail 480 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(6) UniProt(4)
Polymorphisms RFLP(1) : SNPs within 2kb(693 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006028 Gamma-aminobutyric acid A receptor
InterPro IPR008127 Glycine receptor alpha
InterPro IPR008130 Glycine receptor alpha3
InterPro IPR006201 Neurotransmitter-gated ion-channel
InterPro IPR018000 Neurotransmitter-gated ion-channel, conserved site
InterPro IPR006202 Neurotransmitter-gated ion-channel ligand-binding
InterPro IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
Protein Ontology PR:000008044 glycine receptor subunit alpha-3
References (Earliest) J:11417 Derry JM, et al., Mapping of the glycine receptor alpha 2-subunit gene and the GABAA alpha 3-subunit gene on the mouse X chromosome. Genomics. 1991 Jul;10(3):593-7
(Latest) J:191676 Manceau V, et al., The protein kinase KIS impacts gene expression during development and fear conditioning in adult mice. PLoS One. 2012;7(8):e43946
All references(46)
Other
accession IDs
MGD-MRK-10132

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/08/2014
MGI 5.17
The Jackson Laboratory