About   Help   FAQ
Gjb5
Gene Detail
Symbol

Name
ID
Gjb5
gap junction protein, beta 5
MGI:95723
Synonyms
Cnx31.1, connexin 31.1, Cx31.1, Gjb-5
Feature Type
protein coding gene
Genetic Map
Chromosome 4
61.51 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr4:127354809-127358181 bp, - strand
From VEGA annotation of GRCm38

  3373 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3858  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Gjb5

Human
homologs
Human Homolog GJB5, gap junction protein, beta 5, 31.1kDa
NCBI Gene ID 2709
neXtProt AC  NX_O95377
Human Synonyms  CX31.1
Human Chr (Location)  1p35.1; chr1:34755047-34758512 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(20) Targeted(2)
 
Mice homozygous for a null allele exhibit some embryonic lethality, reduced weight and reduced placental development.
 
Interactions
Gjb5 interacts with 83 markers (Mir1b, Mir27a, Mir27b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell communication, labyrinthine layer morphogenesis, ...
Component cell junction, connexon complex, ...
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (11)    Tissues (7)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 5
RT-PCR 6
cDNA source data(37)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(45) Genomic(3) cDNA(37) Primer pair(4) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000009375 (Evidence)
Ensembl Gene ModelENSMUSG00000042357 (Evidence)
Entrez Gene14622 (Evidence)
UniGene26859
DFCITC1582580
DoTSDT.530987
NIA Mouse Gene IndexU025534
Consensus CDS ProjectCCDS18670.1
International Mouse Knockout Project StatusGjb5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009375 VEGA Gene Model | MGI Sequence Detail 3373 C57BL/6J ±  kb
transcript OTTMUST00000021352 VEGA | MGI Sequence Detail 1721 Not Applicable 
polypeptide OTTMUSP00000009765 VEGA | MGI Sequence Detail 271 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(5)
Polymorphisms
RFLP(1) : SNPs within 2kb(43 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000500 Connexin
InterPro IPR017990 Connexin, conserved site
InterPro IPR013092 Connexin, N-terminal
InterPro IPR002270 Gap junction beta-4 protein (Cx31.1)
InterPro IPR019570 Gap junction protein, cysteine-rich domain
Protein Ontology PR:000008001 gap junction beta-5 protein
References
(Earliest) J:2128 Hennemann H, et al., Two gap junction genes, connexin 31.1 and 30.3, are closely linked on mouse chromosome 4 and preferentially expressed in skin. J Biol Chem. 1992 Aug 25;267(24):17225-33
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(44)
Other
accession IDs
MGD-MRK-10095, MGD-MRK-10100

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory