Homozygotes for a spontaneous null mutation exhibit reduced growth from 2 weeks of age, impaired growth hormone synthesis and release, obesity, decreased bone mass, reduced fertility in males, impaired first lactations, and extended life span.
|Process||activation of adenylate cyclase activity, adenohypophysis development, ...|
|Component||cell surface, cytoplasm, ...|
|Function||G-protein coupled receptor activity, growth factor binding, ...|
|InterPro||IPR001879||GPCR, family 2, extracellular hormone receptor domain|
|InterPro||IPR003288||GPCR, family 2, growth hormone-releasing hormone receptor|
|InterPro||IPR017981||GPCR, family 2-like|
|InterPro||IPR000832||GPCR, family 2, secretin-like|
|InterPro||IPR017983||GPCR, family 2, secretin-like, conserved site|
|Protein Ontology||PR:000007972||growth hormone-releasing hormone receptor|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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