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B4galt1
Gene Detail
 Symbol
Name
ID
B4galt1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
MGI:95705
Synonyms b1,4-Galactosyltransferase I, B-1,4-GalT1, beta 1,4-Galactosyltransferase I, beta-1,4-GalT1, GalT, Ggtb, Ggtb2
Feature Type protein coding gene
Genetic Map
Chromosome 4
20.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(13)
Sequence Map
Chr4:40804602-40854005 bp, - strand
From VEGA annotation of GRCm38

  49404 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20378  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: beta-1,4-galactosyltransferase, B4GalT1-6 types
Gene Tree: B4galt1

Human
homologs
Human Homolog B4GALT1, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
NCBI Gene ID 2683
neXtProt AC  NX_P15291
Human Synonyms  B4GAL-T1, beta4Gal-T1, CDG2D, GGTB2, GT1, GTB
Human Chr (Location)  9p13; chr9:33110641-33167358 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human B4GALT1
Mutations,
alleles, and
phenotypes
All mutations/alleles(55) : Gene trapped(49) Targeted(6)
Incidental mutations (data from APF )
 
Homozygotes for targeted null mutations exhibit growth retardation, low viability, excessive epithelial cell proliferation of skin and small intestine, sperm with reduced fertilizing capacity, birthing difficulty, and mammary gland defects.
 
Interactions
B4galt1 interacts with 298 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (103 annotations)
Process acute inflammatory response, angiogenesis involved in wound healing, ...
Component basolateral plasma membrane, brush border membrane, ...
Function 1,2-dihydroxy-phenanthrene glycosyltransferase activity, 1-phenanthrol glycosyltransferase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (120)    Tissues (108)    Images (4)
Theiler Stages: 17, 19, 22, 25, 26, 28
Assay TypeResults
RNA in situ 96
Northern blot 22
RT-PCR 2
cDNA source data(172)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(181) Genomic(1) cDNA(177) Primer pair(2) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000006610 (Evidence)
Ensembl Gene ModelENSMUSG00000028413 (Evidence)
Entrez Gene14595 (Evidence)
UniGene15622
DFCITC1622642, TC1723644
DoTSDT.535043
NIA Mouse Gene IndexU024962
EC2.4.1.-, 2.4.1.22, 2.4.1.38, 2.4.1.90
Consensus CDS ProjectCCDS18051.1
International Mouse Knockout Project StatusB4galt1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006610 VEGA Gene Model | MGI Sequence Detail 49404 C57BL/6J ±  kb
transcript OTTMUST00000015075 VEGA | MGI Sequence Detail 3983 Not Applicable 
polypeptide OTTMUSP00000006967 VEGA | MGI Sequence Detail 399 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(4) UniProt(7)
Polymorphisms RFLP(3) : SNPs within 2kb(144 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003859 Galactosyltransferase, metazoa
Protein Ontology PR:000004605 beta-1,4-galactosyltransferase 1
References (Earliest) J:8592 Shaper NL, et al., The gene for galactosyltransferase maps to mouse chromosome 4. Cytogenet Cell Genet. 1987;44(1):18-21
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(91)
Other
accession IDs
MGD-MRK-10067, MGI:2140118, MGI:891991

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory