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B4galt1
Gene Detail
Symbol

Name
ID
B4galt1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
MGI:95705
Synonyms
b1,4-Galactosyltransferase I, B-1,4-GalT1, beta 1,4-Galactosyltransferase I, beta-1,4-GalT1, GalT, Ggtb, Ggtb2
Feature Type
protein coding gene
Genetic Map
Chromosome 4
20.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(13)
Sequence Map
Chr4:40804602-40854005 bp, - strand
From VEGA annotation of GRCm38

  49404 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20378  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 western clawed frog; 1 zebrafish

HCOP human homology predictions: B4GALT1
Protein SuperFamily: beta-1,4-galactosyltransferase, B4GalT1-6 types
Gene Tree: B4galt1

Human
homologs
B4GALT1, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 2683
neXtProt AC: NX_P15291

Human Synonyms: B4GAL-T1, beta4Gal-T1, CDG2D, GGTB2, GT1, GTB

Human Chr (Location): 9p13; chr9:33110637-33167358 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human B4GALT1

Mutations,
alleles, and
phenotypes
All mutations/alleles(56) : Gene trapped(49) Targeted(7)
Incidental mutations (data from APF , CvDC )
 
Homozygotes for targeted null mutations exhibit growth retardation, low viability, excessive epithelial cell proliferation of skin and small intestine, sperm with reduced fertilizing capacity, birthing difficulty, and mammary gland defects.
 
Interactions
B4galt1 interacts with 298 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Expression
Literature Summary: (5 records)
Data Summary: Results (120)    Tissues (109)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 96
Northern blot 22
RT-PCR 2
cDNA source data(172)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase b4galt1.1, b4galt1.2 ; ZFIN b4galt1    NEW 
Molecular
reagents
All nucleic(181) Genomic(1) cDNA(177) Primer pair(2) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000006610 (Evidence)
Ensembl Gene Model ENSMUSG00000028413 (Evidence)
Entrez Gene 14595 (Evidence)
UniGene 15622
DFCI TC1622642, TC1723644
DoTS DT.535043
NIA Mouse Gene Index U024962
EC 2.4.1.-, 2.4.1.22, 2.4.1.38, 2.4.1.90
Consensus CDS Project CCDS18051.1
International Mouse Phenotyping Consortium Status B4galt1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006610 VEGA Gene Model | MGI Sequence Detail 49404 C57BL/6J ±  kb
transcript OTTMUST00000015075 VEGA | MGI Sequence Detail 3983 Not Applicable 
polypeptide OTTMUSP00000006967 VEGA | MGI Sequence Detail 399 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(4) UniProt(7)
Polymorphisms
RFLP(3) : SNPs within 2kb(144 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003859 Galactosyltransferase, metazoa
Protein Ontology PR:000004605 beta-1,4-galactosyltransferase 1
References
(Earliest) J:8592 Shaper NL, et al., The gene for galactosyltransferase maps to mouse chromosome 4. Cytogenet Cell Genet. 1987;44(1):18-21
(Latest) J:217719 Orr SL, et al., A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins. Glycobiology. 2013 Mar;23(3):363-80
All references(89)
Other
accession IDs
MGD-MRK-10067, MGI:2140118, MGI:891991

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory