Gda
Gene Detail

Symbol Name ID

Gda guanine deaminase MGI:95678

Feature Type

protein coding gene

Genetic Map

Chromosome 19

14.32 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr19:21391307-21473445 bp, - strand From VEGA annotation of GRCm38   82139 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:3171  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: metal-dependent hydrolase (amidohydrolase)
Gene Tree: Gda

Human homologs

Human Homolog		GDA, guanine deaminase
NCBI Gene ID		9615
neXtProt AC		NX_Q9Y2T3
Human Synonyms		CYPIN, GUANASE, NEDASIN
Human Chr (Location)		9q21.13; chr9:74729511-74867140 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	guanine catabolic process
Function	guanine deaminase activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (117)    Tissues (99)    Images (13)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	117

cDNA source data(57)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(59) cDNA(59)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000028318 (Evidence)
Ensembl Gene Model	ENSMUSG00000058624 (Evidence)
Entrez Gene	14544 (Evidence)
UniGene	45054
DFCI	TC1577122, TC1581927
DoTS	DT.101166212, DT.101359497, DT.101362496, DT.101720441, DT.87067836, DT.91579760
NIA Mouse Gene Index	U038910
EC	3.5.4.3
Consensus CDS Project	CCDS29698.1
International Mouse Knockout Project Status	Gda

Sequences

Length	Strain/Species
genomic	OTTMUSG00000028318	VEGA Gene Model | MGI Sequence Detail	82139	C57BL/6J
transcript	OTTMUST00000070187	VEGA | MGI Sequence Detail	5428	Not Applicable
polypeptide	OTTMUSP00000035739	VEGA | MGI Sequence Detail	454	Not Applicable

All sequences(58) RefSeq(2) UniProt(8)

Polymorphisms

SNPs(844 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR006680	Amidohydrolase 1
InterPro	IPR014311	Guanine deaminase
Protein Ontology	PR:000007911	guanine deaminase

References

(Earliest) J:7470 Bonhomme F, et al., Biochemical diversity and evolution in the genus Mus. Biochem Genet. 1984 Apr;22(3-4):275-303
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)

Other accession IDs

MGD-MRK-10024, MGI:2147637, MGI:2147689