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Gda
Gene Detail
 Symbol
Name
ID
Gda
guanine deaminase
MGI:95678
Feature Type protein coding gene
Genetic Map
Chromosome 19
14.32 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr19:21391307-21473445 bp, - strand
From VEGA annotation of GRCm38

  82139 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3171  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: metal-dependent hydrolase (amidohydrolase)
Gene Tree: Gda

Human
homologs
Human Homolog GDA, guanine deaminase
NCBI Gene ID 9615
neXtProt AC  NX_Q9Y2T3
Human Synonyms  CYPIN, GUANASE, NEDASIN
Human Chr (Location)  9q21.13; chr9:72114595-72254822 (+)  GRCh38
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process guanine catabolic process
Component extracellular vesicular exosome
Function guanine deaminase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (117)    Tissues (99)    Images (13)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 117
cDNA source data(58)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(60) cDNA(60)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000028318 (Evidence)
Ensembl Gene ModelENSMUSG00000058624 (Evidence)
Entrez Gene14544 (Evidence)
UniGene45054
DFCITC1577122, TC1581927
DoTSDT.101166212, DT.101359497, DT.101362496, DT.101720441, DT.87067836, DT.91579760
NIA Mouse Gene IndexU038910
EC3.5.4.3
Consensus CDS ProjectCCDS29698.1
International Mouse Knockout Project StatusGda
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028318 VEGA Gene Model | MGI Sequence Detail 82139 C57BL/6J ±  kb
transcript OTTMUST00000070187 VEGA | MGI Sequence Detail 5428 Not Applicable 
polypeptide OTTMUSP00000035739 VEGA | MGI Sequence Detail 454 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(4) UniProt(8)
Polymorphisms SNPs within 2kb(1622 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006680 Amidohydrolase 1
InterPro IPR014311 Guanine deaminase
InterPro IPR011059 Metal-dependent hydrolase, composite domain
Protein Ontology PR:000007911 guanine deaminase
References (Earliest) J:7470 Bonhomme F, et al., Biochemical diversity and evolution in the genus Mus. Biochem Genet. 1984 Apr;22(3-4):275-303
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)
Other
accession IDs
MGD-MRK-10024, MGI:2147637, MGI:2147689

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory