Homozygous inactivation is embryonic lethal and show a variety of embryonic defects. T cell development is impaired when the locus is conditionally. Mice with a spontaneous mutation exhibit partial hair loss and various defects in hair structure and in hair growth cycle regulation.
|Process||anatomical structure formation involved in morphogenesis, aortic valve morphogenesis, ...|
|Component||cell, intracellular, ...|
|Function||core promoter proximal region sequence-specific DNA binding, core promoter sequence-specific DNA binding, ...|
|RNA in situ||663|
|In situ reporter (knock in)||23|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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