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Gapdhs
Gene Detail
Symbol

Name
ID
Gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
MGI:95653
Synonyms
Gapds, Gapd-s
Feature Type
protein coding gene
Genetic Map
Chromosome 7
19.23 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:30729775-30743681 bp, - strand
From VEGA annotation of GRCm38

  13907 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:101265  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

HCOP human homology predictions: GAPDHS
Protein SuperFamily: glyceraldehyde-3-phosphate dehydrogenase
Gene Tree: Gapdhs

Human
homologs
GAPDHS, glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 26330
neXtProt AC: NX_O14556

Human Synonyms: GAPD2, GAPDH-2, GAPDS, HSD-35

Human Chr (Location): 19q13.12; chr19:35533412-35545319 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(2) Targeted(4)
Incidental mutations (data from APF )
 
Homozygous null mice display male infertility and asthenozoospermia.
 
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process glucose metabolic process, glycolytic process, ...
Component cilium, cytoplasm, ...
Function glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, NAD binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (119)    Tissues (98)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 119
cDNA source data(25)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(27) cDNA(25) Primer pair(1) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000043090 (Evidence)
Ensembl Gene Model ENSMUSG00000061099 (Evidence)
Entrez Gene 14447 (Evidence)
UniGene 436562
DFCI TC1586023
DoTS DT.40185851
NIA Mouse Gene Index U028399
EC 1.2.1.12
Consensus CDS Project CCDS21109.1, CCDS71933.1
International Mouse Phenotyping Consortium Status Gapdhs
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000043090 VEGA Gene Model | MGI Sequence Detail 13907 C57BL/6J ±  kb
transcript OTTMUST00000113074 VEGA | MGI Sequence Detail 1457 Not Applicable 
polypeptide OTTMUSP00000063310 VEGA | MGI Sequence Detail 440 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(8) UniProt(4)
Polymorphisms
SNPs within 2kb(203 from dbSNP Build 137)    SNPs within 2kb including multiple locations(221)
Protein-related
information
ResourceIDDescription
InterPro IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site
InterPro IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
InterPro IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
InterPro IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I
InterPro IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family
InterPro IPR016040 NAD(P)-binding domain
Protein Ontology PR:000007841 glyceraldehyde-3-phosphate dehydrogenase, testis-specific
References
(Earliest) J:843 Welch JE, et al., Expression of a glyceraldehyde 3-phosphate dehydrogenase gene specific to mouse spermatogenic cells. Biol Reprod. 1992 May;46(5):869-78
(Latest) J:193996 Chauvin T, et al., A systematic analysis of a deep mouse epididymal sperm proteome. Biol Reprod. 2012;87(6):141
All references(39)
Other
accession IDs
MGD-MRK-9980, MGD-MRK-9981

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory