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Gabrr2
Gene Detail
 Symbol
Name
ID
Gabrr2
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
MGI:95626
Feature Type protein coding gene
Genetic Map
Chromosome 4
14.64 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr4:33062999-33095865 bp, + strand
From VEGA annotation of GRCm38

  32867 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20471  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Gabrr2

Human
homologs
Human Homolog GABRR2, gamma-aminobutyric acid (GABA) A receptor, rho 2
NCBI Gene ID 2570
neXtProt AC  NX_P28476
Human Chr (Location)  6q15; chr6:89257121-89315299 (-)  GRCh38
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process chloride transport, gamma-aminobutyric acid signaling pathway, ...
Component axon, cell junction, ...
Function chloride channel activity, extracellular ligand-gated ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (56)    Tissues (32)    Images (10)
Theiler Stages: 19, 23, 25, 26, 28
Assay TypeResults
RNA in situ 30
Western blot 3
RT-PCR 23
cDNA source data(9)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(11) cDNA(9) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000004918 (Evidence)
Ensembl Gene ModelENSMUSG00000023267 (Evidence)
Entrez Gene14409 (Evidence)
UniGene6227
DFCITC1588361
DoTSDT.101165182, DT.40182495
NIA Mouse Gene IndexU004172
Consensus CDS ProjectCCDS18020.1
International Mouse Knockout Project StatusGabrr2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004918 VEGA Gene Model | MGI Sequence Detail 32867 C57BL/6J ±  kb
transcript OTTMUST00000010945 VEGA | MGI Sequence Detail 1933 Not Applicable 
polypeptide OTTMUSP00000005112 VEGA | MGI Sequence Detail 465 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(6) UniProt(4)
Polymorphisms RFLP(2) : SNPs within 2kb(275 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006028 Gamma-aminobutyric acid A receptor
InterPro IPR008057 Gamma-aminobutyric-acid A receptor, Rho
InterPro IPR008059 Gamma-aminobutyric-acid A receptor, Rho2
InterPro IPR006201 Neurotransmitter-gated ion-channel
InterPro IPR018000 Neurotransmitter-gated ion-channel, conserved site
InterPro IPR006202 Neurotransmitter-gated ion-channel ligand-binding
InterPro IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
Protein Ontology PR:000007783 gamma-aminobutyric acid receptor subunit rho-2
References (Earliest) J:2295 Cutting GR, et al., Identification of a putative gamma-aminobutyric acid (GABA) receptor subunit rho2 cDNA and colocalization of the genes encoding rho2 (GABRR2) and rho1 (GABRR1) to human chromosome 6q14-q21 and mouse chromosome 4. Genomics. 1992 Apr;12(4):801-6
(Latest) J:185665 Guo Z, et al., Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20
All references(38)
Other
accession IDs
MGD-MRK-9945

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory