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Gabrr2 Gene Detail
Summary
  • Symbol
    Gabrr2
  • Name
    gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:95626
    NCBI Gene: 14409
  • Gene Overview
    MyGene.info: GABRR2
Location & Maps
more
  • Sequence Map
    Chr4:33062999-33095865 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      32867 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 14.64 cM
  • Mapping Data
    6 experiments
Homology
more
  • Human Ortholog
    GABRR2, gamma-aminobutyric acid type A receptor rho2 subunit
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GABRR2, gamma-aminobutyric acid type A receptor rho2 subunit
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 2570
    neXtProt AC: NX_P28476

  • Chr Location
    6q15; chr6:89256061-89315299 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically and radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Gabrr2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004918 VEGA Gene Model | MGI Sequence Detail 32867 C57BL/6J ±  kb
transcript OTTMUST00000010945 VEGA | MGI Sequence Detail 1933 Not Applicable  
polypeptide OTTMUSP00000005112 VEGA | MGI Sequence Detail 465 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    306 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000007783 gamma-aminobutyric acid receptor subunit rho-2
  • InterPro Domains
    IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alpha
    IPR008057 Gamma-aminobutyric-acid A receptor, Rho
    IPR008059 Gamma-aminobutyric-acid A receptor, Rho2
    IPR006201 Neurotransmitter-gated ion-channel
    IPR018000 Neurotransmitter-gated ion-channel, conserved site
    IPR006202 Neurotransmitter-gated ion-channel ligand-binding domain
    IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
Molecular
Reagents
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  • All nucleic 11
    cDNA 9
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-9945
References
more
  • Summaries
    All 36
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:2295 Cutting GR, et al., Identification of a putative gamma-aminobutyric acid (GABA) receptor subunit rho2 cDNA and colocalization of the genes encoding rho2 (GABRR2) and rho1 (GABRR1) to human chromosome 6q14-q21 and mouse chromosome 4. Genomics. 1992 Apr;12(4):801-6
  • Latest
    J:185665 Guo Z, et al., Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory