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Ftl1
Gene Detail
 Symbol
Name
ID
Ftl1
ferritin light chain 1
MGI:95589
Synonyms Ftl, L-ferritin
Feature Type protein coding gene
Genetic Map
Chromosome 7
29.32 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr7:45457944-45459884 bp, - strand
From VEGA annotation of GRCm38

  1941 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:79330  Vertebrate Homology Class
1 human; 2 mouse; 8 rat; 1 chimpanzee; 3 rhesus macaque; 4 cattle; 2 dog; 1 western clawed frog

Protein SuperFamily: ferritin
Gene Tree: Ftl1

Human
homologs
Human Homolog FTL, ferritin, light polypeptide
NCBI Gene ID 2512
neXtProt AC  NX_P02792
Human Synonyms  LFTD, NBIA3
Human Chr (Location)  19q13.33; chr19:48965309-48966879 (+)  GRCh38
Disease Associations  (3) Diseases Associated with Human FTL
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from APF )
Interactions
Ftl1 interacts with 60 markers (Mir22, Mir92-1, Mir133a-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Component cytoplasm, extracellular vesicular exosome, ...
Function identical protein binding, iron ion binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (14)    Tissues (8)   
Theiler Stages: 17, 20, 24, 28
Assay TypeResults
RNA in situ 12
RT-PCR 2
cDNA source data(38)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(43) Genomic(1) cDNA(41) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000022565 (Evidence)
Ensembl Gene ModelENSMUSG00000050708 (Evidence)
Entrez Gene14325 (Evidence)
DoTSDT.101123906, DT.101374525, DT.101374656, DT.103576057, DT.40170879, DT.91403229, DT.94222407, DT.94235556, DT.99871270
Consensus CDS ProjectCCDS39952.1
International Mouse Knockout Project StatusFtl1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022565 VEGA Gene Model | MGI Sequence Detail 1941 C57BL/6J ±  kb
transcript OTTMUST00000054058 VEGA | MGI Sequence Detail 968 Not Applicable 
polypeptide OTTMUSP00000025746 VEGA | MGI Sequence Detail 183 Not Applicable 

For the selected sequences
All sequences(80) RefSeq(2)
Polymorphisms RFLP(1) : SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000007738 ferritin light chain 1
References (Earliest) J:9732 Beaumont C, et al., Transcriptional regulation of ferritin H and L subunits in adult erythroid and liver cells from the mouse. Unambiguous identification of mouse ferritin subunits and in vitro formation of the ferritin shells. J Biol Chem. 1989 May 5;264(13):7498-504
(Latest) J:176655 Moroishi T, et al., The FBXL5-IRP2 Axis Is Integral to Control of Iron Metabolism In Vivo. Cell Metab. 2011 Sep 7;14(3):339-51
All references(41)
Other
accession IDs
MGD-MRK-9885, MGD-MRK-9886, MGD-MRK-9888

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory